LOCUS       SIU02304.1               104 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 pe-
            pgrs family-related protein pe_pgrs60 protein.
ACCESSION   LT708304-3718
PROTEIN_ID  SIU02304.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="PE_PGRS60"
                     /locus_tag="BQ2027_MB3676"
                     /note="Mb3676, PE_PGRS60, len: 104 aa. Equivalent to
                     Rv3652, len: 104 aa, from Mycobacterium tuberculosis
                     strain H37Rv, (100.0% identity in 104 aa overlap). Member
                     of the Mycobacterium tuberculosis PE family, PGRS
                     subfamily of gly-rich proteins, similar at N-terminal end
                     with many e.g. P56877|Y278_MYCTU|Rv0278c|MTV035.06c (957
                     aa) FASTA scores: opt: 242, E(): 3e-09, (77.35% identity
                     in 53 aa overlap). Originally annotated as the first part
                     of a PE-PGRS family protein (Rv3653/PE_PGRS61 being the
                     second part) but more similar to a PE family protein.
                     Length extended since first submission (+50 aa). Mb3676
                     found to be expressed during exponential growth in
                     Sauton's minimal media by RNA-sequencing (TPM > 20)."
                     /db_xref="InterPro:IPR000084"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y4T4"
BEGIN
        1 MSYVIAAPEA LVAAATDLAT LGSTIGAANA AAAGSTTALL TAGADEVSAA IAAYSECTAR
       61 PIRHSVRGRR RSMSGSCRPW PQVGAPMRPP RPPASRRCRA RSIC
//