LOCUS SIU02293.1 211 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE CELL FILAMENTATION PROTEIN FIC protein. ACCESSION LT708304-3707 PROTEIN_ID SIU02293.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="fic" /locus_tag="BQ2027_MB3665C" /note="Mb3665c, fic, len: 211 aa. Equivalent to Rv3641c, len: 211 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 211 aa overlap). Possible fic, cell filamentation protein, similar to others e.g. Q9PCU8|XF1657 CELL FILAMENTATION PROTEIN from Xylella fastidiosa (203 aa), FASTA scores: opt: 324, E(): 2.2e-14, (32.8% identity in 189 aa overlap); P20605|FIC_ECOLI|B3361 from Escherichia coli strain K12 (200 aa), FASTA scores: opt: 323, E(): 2.5e-14, (31.0% identity in 187 aa overlap); P20751|FIC_SALTY from Salmonella typhimurium (200 aa), FASTA scores: opt: 322, E(): 2.9e-14, (32.65% identity in 193 aa overlap); etc. Mb3665c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="InterPro:IPR003812" /db_xref="InterPro:IPR036597" /db_xref="UniProtKB/TrEMBL:A0A1R3Y4S8" BEGIN 1 MPHPWDTGDH ERNWQGYFIP AMSVLRNRVG ARTHAELRDA ENDLVEARVI ELREDPNLLG 61 DRTDLAYLRA IHRQLFQDIY VWAGDLRTVG IEKEDESFCA PGGISRPMEH VAAEIYQLDR 121 LRAVGEGDLA GQVAYRYDYV NYAHPFREGN GRSTREFFDL LLSERGSGLD WGKTDLEELH 181 GACHVARANS DLTGLVAMFK GILDAEPTYD F //