LOCUS       SIU02293.1               211 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE
            CELL FILAMENTATION PROTEIN FIC protein.
ACCESSION   LT708304-3707
PROTEIN_ID  SIU02293.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="fic"
                     /locus_tag="BQ2027_MB3665C"
                     /note="Mb3665c, fic, len: 211 aa. Equivalent to Rv3641c,
                     len: 211 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 211 aa overlap). Possible fic, cell
                     filamentation protein, similar to others e.g.
                     Q9PCU8|XF1657 CELL FILAMENTATION PROTEIN from Xylella
                     fastidiosa (203 aa), FASTA scores: opt: 324, E(): 2.2e-14,
                     (32.8% identity in 189 aa overlap); P20605|FIC_ECOLI|B3361
                     from Escherichia coli strain K12 (200 aa), FASTA scores:
                     opt: 323, E(): 2.5e-14, (31.0% identity in 187 aa
                     overlap); P20751|FIC_SALTY from Salmonella typhimurium
                     (200 aa), FASTA scores: opt: 322, E(): 2.9e-14, (32.65%
                     identity in 193 aa overlap); etc. Mb3665c found to be
                     expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /db_xref="InterPro:IPR003812"
                     /db_xref="InterPro:IPR036597"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y4S8"
BEGIN
        1 MPHPWDTGDH ERNWQGYFIP AMSVLRNRVG ARTHAELRDA ENDLVEARVI ELREDPNLLG
       61 DRTDLAYLRA IHRQLFQDIY VWAGDLRTVG IEKEDESFCA PGGISRPMEH VAAEIYQLDR
      121 LRAVGEGDLA GQVAYRYDYV NYAHPFREGN GRSTREFFDL LLSERGSGLD WGKTDLEELH
      181 GACHVARANS DLTGLVAMFK GILDAEPTYD F
//