LOCUS SIU02290.1 248 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 possible transposase protein. ACCESSION LT708304-3704 PROTEIN_ID SIU02290.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB3662" /note="Mb3662, -, len: 248 aa. Equivalent to Rv3638, len: 248 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 248 aa overlap). Possible transposase, highly similar to Q9RLQ8|ISTB ISTB PROTEIN from Mycobacterium bovis (266 aa), FASTA scores: opt: 784, E(): 4e-46, (78.0% identity in 259 aa overlap); and similar to others e.g. P15026|ISTB_PSEAE INSERTION SEQUENCE IS21 PUTATIVE ATP-BINDING PROTEIN from Pseudomonas aeruginosa (265 aa), FASTA scores: opt: 420, E(): 2.2e-21, (38.8% identity in 255 aa overlap); Q45619|ISTB_BACST INSERTION SEQUENCE IS5376 PUTATIVE ATP-BINDING PROTEIN from Bacillus stearothermophilus (251 aa), FASTA scores: opt: 402, E(): 3.6e-20, (34.5% identity in 232 aa overlap); P15026|ISTB_ECOLI ISTB PROTEIN from Escherichia coli (265 aa), FASTA scores: opt: 419, E(): 8e-23, (38.8% identity in 255 aa overlap); etc. C-terminus highly similar to C-terminus of P96287|Rv2944|MTCY24G1.05 HYPOTHETICAL 25.5 KDA PROTEIN from Mycobacterium tuberculosis strain H37Rv (alias AAK47343|MT3016 IS1533, ORFB from Mycobacterium tuberculosis strain CDC1551) (238 aa), FASTA scores: opt: 784, E(): 3.6e-46, (87.4% identity in 135 aa overlap)." /db_xref="GOA:A0A1R3Y4P5" /db_xref="InterPro:IPR002611" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR028350" /db_xref="UniProtKB/TrEMBL:A0A1R3Y4P5" BEGIN 1 MAAKTATNSR DVAAELAYLT RALKAPTLRG AIEQLADRAR TKTWSYEEFL AACLQREVSA 61 RESHGGEGRI RAARFPSRKS LEEFDFDHAR GLKRDTIAHL GTLDFVTLAI GIAIRACQAG 121 HRVLFATASQ WVDRLAAAHH SGTLQSELIR LARYPLLVVD EVGYIPFEPE AANLFFQLVS 181 SRYERASLIV TSNKPFGRWG EVFGDDVVAA AMIDRLVHHA EVIALKGDSY RIKDRDLGRV 241 PTVTADDQ //