LOCUS       SIU02278.1               350 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 proteolysis/
            nucleotide biosynthesis protein.
ACCESSION   LT708304-3692
PROTEIN_ID  SIU02278.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB3650C"
                     /note="Mb3650c, -, len: 350 aa. Equivalent to Rv3626c,
                     len: 350 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 350 aa overlap). Conserved
                     hypothetical protein, similar to Q9X8I7|SCE9.14c
                     HYPOTHETICAL PROTEIN from Streptomyces coelicolor (375 aa)
                     FASTA scores: opt: 720, E(): 2.2e-38, (41.55% identity in
                     361 aa overlap); and shows some similarity to
                     Q9HPS0|VNG1497C HYPOTHETICAL PROTEIN (317 aa) FASTA
                     scores: opt: 226, E(): 4.5e-07, (29.7% identity in 347 aa
                     overlap). Contains neutral zinc metallopeptidases,
                     zinc-binding region signature (PS00142). Protein product
                     from Mb3650c detected using shotgun mass spectrometry and
                     SWATH mass spectrometry. Mb3650c found to be expressed
                     during exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="InterPro:IPR018766"
                     /db_xref="InterPro:IPR022454"
                     /db_xref="InterPro:IPR042271"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y4S6"
BEGIN
        1 MTGASELTLG NTVDWEFAAS VGERLARPAP PSTEYTRRQV IDELTVAAEK AEPPVRDVTG
       61 LIADGVVPPA RVVDRPAWIR SAAESMRAMT HGSAKPRGFL TGRITGAQTG AVLAFVASGI
      121 LGQYDPFGAA GEGCLLLVYP NVIAVERQLR VEPSDFRLWV CLHEVTHRVQ FTANPWLSGY
      181 MSQALNLLTF EPVDDIGRVV SRLADFIRSR GHGTDDSEVN PSGILGLVRA VQSEPQRKAL
      241 DQLLVLGTLL EGHAEHVMDA VGPMVVPSVA TIRRRFDDRR HHKQPPLQRL VRALLGFDAK
      301 LSQYTRGKAF VDHVVDRAGM KLFNTIWSGP ETLPLPAEIE NPQRWIDRVL
//