LOCUS       SIU02263.1               158 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            CONSERVED SECRETED PROTEIN protein.
ACCESSION   LT708304-3677
PROTEIN_ID  SIU02263.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB3635C"
                     /note="Mb3635c, -, len: 158 aa. Equivalent to Rv3605c,
                     len: 158 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 158 aa overlap). Probable conserved
                     secreted or membrane protein, identical to
                     O69527|MLCB2548.04c|ML0227 PUTATIVE MEMBRANE PROTEIN from
                     Mycobacterium leprae (158 aa), FASTA scores: opt: 944,
                     E(): 2.6e-56, (85.45% identity in 158 aa overlap). Also
                     similar to other proteins e.g. Q9X8I2|SCE9.09 POSSIBLE
                     SECRETED PROTEIN from Streptomyces coelicolor (162 aa),
                     FASTA scores: opt: 174, E(): 9.2e-05, (31.25% identity in
                     128 aa overlap); etc. Contains possible N-terminal signal
                     sequence. Protein product from Mb3635c detected using
                     SWATH mass spectrometry. Mb3635c found to be expressed
                     during exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:A0A1R3Y4M6"
                     /db_xref="InterPro:IPR021517"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y4M6"
BEGIN
        1 MGPTRKRDLT AAVVGAAAVG YLLVAVLYRW FPPITVWTGL SLLAVAVAEA LWARYVRVKI
       61 SDGEIGDGPG WLHPLVVARS LMVAKASAWV GALVTGWWIG VLAYFLPRRS WLRAAAEDTT
      121 GTVVAAGSAL ALVVAALWLQ HCCKSPQDPT EHADGAES
//