LOCUS SIU02263.1 158 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE CONSERVED SECRETED PROTEIN protein. ACCESSION LT708304-3677 PROTEIN_ID SIU02263.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB3635C" /note="Mb3635c, -, len: 158 aa. Equivalent to Rv3605c, len: 158 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 158 aa overlap). Probable conserved secreted or membrane protein, identical to O69527|MLCB2548.04c|ML0227 PUTATIVE MEMBRANE PROTEIN from Mycobacterium leprae (158 aa), FASTA scores: opt: 944, E(): 2.6e-56, (85.45% identity in 158 aa overlap). Also similar to other proteins e.g. Q9X8I2|SCE9.09 POSSIBLE SECRETED PROTEIN from Streptomyces coelicolor (162 aa), FASTA scores: opt: 174, E(): 9.2e-05, (31.25% identity in 128 aa overlap); etc. Contains possible N-terminal signal sequence. Protein product from Mb3635c detected using SWATH mass spectrometry. Mb3635c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:A0A1R3Y4M6" /db_xref="InterPro:IPR021517" /db_xref="UniProtKB/TrEMBL:A0A1R3Y4M6" BEGIN 1 MGPTRKRDLT AAVVGAAAVG YLLVAVLYRW FPPITVWTGL SLLAVAVAEA LWARYVRVKI 61 SDGEIGDGPG WLHPLVVARS LMVAKASAWV GALVTGWWIG VLAYFLPRRS WLRAAAEDTT 121 GTVVAAGSAL ALVVAALWLQ HCCKSPQDPT EHADGAES //