LOCUS SIU02255.1 112 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 iron- regulated h-ns-like protein lsr2 protein. ACCESSION LT708304-3669 PROTEIN_ID SIU02255.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="lsr2" /locus_tag="BQ2027_MB3628C" /note="Mb3628c, lsr2, len: 112 aa. Equivalent to Rv3597c, len: 112 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 112 aa overlap). Probable lsr2, identical to P24094|LSR2_MYCLE|ML0234 LSR2 PROTEIN PRECURSOR (15 KDA ANTIGEN) (A15) from Mycobacterium leprae (112 aa), FASTA scores: opt: 698, E(): 6.7e-37, (92.85% identity in 112 aa overlap). Also highly similar to others e.g. Q9X8N1|SCE94.26c from Streptomyces coelicolor (111 aa), FASTA scores: opt: 379, E(): 4.4e-17, (58.05% identity in 112 aa overlap); Q9ETI2|LSR2 from Corynebacterium equii (Rhodococcus equi) (119 aa), FASTA scores: opt: 328, E(): 6.9e-14, (47.5% identity in 120 aa overlap); and Q9RKK8|SCD25.12c from Streptomyces coelicolor (105 aa), FASTA scores: opt: 293, E(): 9.4e-12, (47.75% identity in 111 aa overlap). Protein product from Mb3628c detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb3628c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:P65649" /db_xref="InterPro:IPR024412" /db_xref="InterPro:IPR042254" /db_xref="InterPro:IPR042261" /db_xref="UniProtKB/Swiss-Prot:P65649" /experiment="experimental evidence, no additional details recorded" BEGIN 1 MAKKVTVTLV DDFDGSGAAD ETVEFGLDGV TYEIDLSTKN ATKLRGDLKQ WVAAGRRVGG 61 RRRGRSGSGR GRGAIDREQS AAIREWARRN GHNVSTRGRI PADVIDAYHA AT //