LOCUS SIU02250.1 105 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 possible heme degrading protein mhud protein. ACCESSION LT708304-3664 PROTEIN_ID SIU02250.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="mhud" /locus_tag="BQ2027_MB3623" /note="Mb3623, TB11.2, len: 105 aa. Equivalent to Rv3592, len: 105 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 105 aa overlap). TB11.2, conserved hypothetical protein (see citations from 2000 below), equivalent to Q9CBI8|ML1922 HYPOTHETICAL PROTEIN from Mycobacterium leprae (105 aa) FASTA scores: opt: 591, E(): 2.5e-34, (84.6% identity in 104 aa overlap). Shows some similarity with other bacterial hypothetical proteins e.g. Q9RXN8|DR0272 from Deinococcus radiodurans (109 aa), FASTA scores: opt: 178, E(): 1e-05, (34.3% identity in 102 aa overlap); P38049|YHGC_BACSU from Bacillus subtilis (166 aa) FASTA scores: opt: 175, E(): 2.4e-05, (40.85% identity in 71 aa overlap); Q9K649|BH3883 from Bacillus halodurans (102 aa) FASTA scores: opt: 162, E(): 0.00012, (33.75% identity in 80 aa overlap); etc. Protein product from Mb3623 detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb3623 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="InterPro:IPR007138" /db_xref="InterPro:IPR011008" /db_xref="UniProtKB/TrEMBL:A0A1R3Y4L7" /experiment="experimental evidence, no additional details recorded" BEGIN 1 MPVVKINAIE VPAGAGPELE KRFAHRAHAV ENSPGFLGFQ LLRPVKGEER YFVVTHWESD 61 EAFQAWANGP AIAAHAGHRA NPVATGASLL EFEVVLDVGG TGKTA //