LOCUS       SIU02245.1               264 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            CONSERVED MEMBRANE PROTEIN protein.
ACCESSION   LT708304-3659
PROTEIN_ID  SIU02245.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB3618C"
                     /note="Mb3618c, -, len: 264 aa. Equivalent to Rv3587c,
                     len: 264 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 264 aa overlap). Probable conserved
                     membrane protein, equivalent to Q9CBJ2|ML1918 HYPOTHETICAL
                     MEMBRANE PROTEIN from Mycobacterium leprae (263 aa), FASTA
                     scores: opt: 1438, E(): 2.4e-57, (77.55% identity in 267
                     aa overlap). Contains hydrophobic stretch in N-terminus;
                     possible signal sequence. Protein product from Mb3618c
                     detected using shotgun mass spectrometry and SWATH mass
                     spectrometry. Mb3618c found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:A0A1R3Y682"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y682"
BEGIN
        1 MLDLEPRGPL PTEIYWRRRG LALGIAVVVV GIAVAIVIAF VDSSAGAKPV SADKPASAQS
       61 HPGSPAPQAP QPAGQTEGNA AAAPPQGQNP ETPTPTAAVQ PPPVLKEGDD CPDSTLAVKG
      121 LTNAPQYYVG DQPKFTMVVT NIGLVSCKRD VGAAVLAAYV YSLDNKRLWS NLDCAPSNET
      181 LVKTFSPGEQ VTTAVTWTGM GSAPRCPLPR PAIGPGTYNL VVQLGNLRSL PVPFILNQPP
      241 PPPGPVPAPG PAQAPPPESP AQGG
//