LOCUS SIU02242.1 182 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE CONSERVED LIPOPROTEIN LPQE protein. ACCESSION LT708304-3656 PROTEIN_ID SIU02242.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="lpqE" /locus_tag="BQ2027_MB3615" /note="Mb3615, lpqE, len: 182 aa. Equivalent to Rv3584, len: 182 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 182 aa overlap). Possible lpqE, conserved lipoprotein, equivalent to Q9ZBM7|MLCB1450.02|LPQE|ML0319 PUTATIVE LIPOPROTEIN from Mycobacterium leprae (183 aa), FASTA scores: opt: 722, E(): 6.2e-37, (63.45% identity in 175 aa overlap). Also similar in part to Q9KK69 EXPORTED PROTEIN 996A010 (FRAGMENT) from Mycobacterium avium (41 aa), FASTA scores: opt: 180, E(): 0.00012, (69.25% identity in 39 aa overlap); and Q9L0R0|SCD8A.04c PUTATIVE LIPOPROTEIN from Streptomyces coelicolor (241 aa), FASTA scores: opt: 127, E(): 0.86, (27.15% identity in 173 aa overlap). Equivalent to AAK48048 from Mycobacterium tuberculosis strain CDC1551 (238 aa) but shorter 56 aa. Contains probable N-terminal signal sequence and appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site. Protein product from Mb3615 detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb3615 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing (TPM > 20)." /db_xref="GOA:P65309" /db_xref="UniProtKB/Swiss-Prot:P65309" BEGIN 1 MNRCNIRLRL AGMTTWVASI ALLAAALSGC GAGQISQTAN QKPAVNGNRL TINNVLLRDI 61 RIQAVQTSDF IQPGKAVDLV LVAVNQSPDV SDRLVGITSD IGSVTVAGDA RLPASGMLFV 121 GTPDGQIVAP GPLPSNQAAK ATVNLTKPIA NGLTYNFTFK FEKAGQGSVM VPISAGLATP 181 HE //