LOCUS       SIU02242.1               182 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE
            CONSERVED LIPOPROTEIN LPQE protein.
ACCESSION   LT708304-3656
PROTEIN_ID  SIU02242.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="lpqE"
                     /locus_tag="BQ2027_MB3615"
                     /note="Mb3615, lpqE, len: 182 aa. Equivalent to Rv3584,
                     len: 182 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 182 aa overlap). Possible lpqE,
                     conserved lipoprotein, equivalent to
                     Q9ZBM7|MLCB1450.02|LPQE|ML0319 PUTATIVE LIPOPROTEIN from
                     Mycobacterium leprae (183 aa), FASTA scores: opt: 722,
                     E(): 6.2e-37, (63.45% identity in 175 aa overlap). Also
                     similar in part to Q9KK69 EXPORTED PROTEIN 996A010
                     (FRAGMENT) from Mycobacterium avium (41 aa), FASTA scores:
                     opt: 180, E(): 0.00012, (69.25% identity in 39 aa
                     overlap); and Q9L0R0|SCD8A.04c PUTATIVE LIPOPROTEIN from
                     Streptomyces coelicolor (241 aa), FASTA scores: opt: 127,
                     E(): 0.86, (27.15% identity in 173 aa overlap). Equivalent
                     to AAK48048 from Mycobacterium tuberculosis strain CDC1551
                     (238 aa) but shorter 56 aa. Contains probable N-terminal
                     signal sequence and appropriately positioned PS00013
                     Prokaryotic membrane lipoprotein lipid attachment site.
                     Protein product from Mb3615 detected using shotgun mass
                     spectrometry and SWATH mass spectrometry. Mb3615 found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing (TPM > 20)."
                     /db_xref="GOA:P65309"
                     /db_xref="UniProtKB/Swiss-Prot:P65309"
BEGIN
        1 MNRCNIRLRL AGMTTWVASI ALLAAALSGC GAGQISQTAN QKPAVNGNRL TINNVLLRDI
       61 RIQAVQTSDF IQPGKAVDLV LVAVNQSPDV SDRLVGITSD IGSVTVAGDA RLPASGMLFV
      121 GTPDGQIVAP GPLPSNQAAK ATVNLTKPIA NGLTYNFTFK FEKAGQGSVM VPISAGLATP
      181 HE
//