LOCUS SIU02237.1 322 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 possible trna/rrna methyltransferase protein. ACCESSION LT708304-3651 PROTEIN_ID SIU02237.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB3610C" /note="Mb3610c, -, len: 322 aa. Equivalent to Rv3579c, len: 322 aa, from Mycobacterium tuberculosis strain H37Rv, (99% identity in 322 aa overlap). Putative tRNA/rRNA methyltransferase (EC 2.1.1.-), equivalent, but longer, to Q9CCW4|ML0324 PUTATIVE METHYLTRANSFERASE from Mycobacterium leprae (278 aa), REMARK-M.bovis-M.tuberculosis: In the original M.bovis genome, a single base insertion (*-g) led to a longer product with a different COOH part compared to its homolog in Mycobacterium strain H37Rv (402 aa versus 322 aa). This was corrected in the new M.bovis genome update to a 322aa product Protein product from Mb3610c detected using SWATH mass spectrometry. Mb3610c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:Q7TW55" /db_xref="InterPro:IPR001537" /db_xref="InterPro:IPR004441" /db_xref="InterPro:IPR013123" /db_xref="InterPro:IPR029026" /db_xref="InterPro:IPR029028" /db_xref="InterPro:IPR029064" /db_xref="UniProtKB/Swiss-Prot:Q7TW55" BEGIN 1 MPGNSRRRGA VRKSGTKKGA GVGSGGQRRR GLEGRGPTPP AHLRPHHPAA KRARAQPRRP 61 VKRADETETV LGRNPVLECL RAGVPATALY VALGTEADER LTECVARAAD SGIAIVELLR 121 ADLDRMTANH LHQGIALQVP PYNYAHPDDL LAAALDQPPA LLVALDNLSD PRNLGAIMRS 181 VAAFGGHGVL IPQRRSASVT AVAWRTSAGA AARIPVARAT NLTRTLKGWA DRGVRVIGLD 241 AGGGTALDDV DGTDSLVVVV GSEGKGLSRL VRQNCDEVVS IPMAAQAESL NASVAAGVVL 301 AAIARQRRRP REPREQTQNR MI //