LOCUS       SIU02235.1               288 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Zn-
            dependent hydrolases of the beta-lactamase fold protein.
ACCESSION   LT708304-3649
PROTEIN_ID  SIU02235.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB3608"
                     /note="Mb3608, -, len: 288 aa. Equivalent to Rv3577, len:
                     288 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 288 aa overlap), (other start sites
                     possible upstream; equivalent to AAK48041 from
                     Mycobacterium tuberculosis strain CDC1551 (379 aa) but
                     shorter 91 aa). Hypothetical protein, showing some
                     similarity to Q9RI88|SCJ11.16c HYPOTHETICAL 37.9 KDA
                     PROTEIN from Streptomyces coelicolor (349 aa) FASTA
                     scores: opt: 285, E(): 1.5e-10, (27.45% identity in 266 aa
                     overlap). Mb3608 found to be expressed during exponential
                     growth in Sauton's minimal media by RNA-sequencing (TPM >
                     20)."
                     /db_xref="InterPro:IPR036866"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y662"
BEGIN
        1 MPTARSDAPL SVTWMGVATL LVDDGSSALM TDGYFSRPGL ARVAAGKVSP SAERVDGCLA
       61 RANVSRLTAV IPVHTHIDHA MDSALVADRT GAQLVGGESA ANVGRGYGLP EESLVVAVPG
      121 EPIQLGAFDV TLVESHHCPP DRFPGVISAP LTPPVKASAY RCGEAWSTLV HHRPSGRRLL
      181 IQDSAGFVSG ALAGYRADAA YLSVGQLGLQ PPSYLLEYWT ETVRTVGVRR VILIHWDDFF
      241 RPLSKPLRAL PYAADDLDLS IRILDELAAQ DGVALQMPTV WRREDPWM
//