LOCUS       SIU02234.1               237 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE
            CONSERVED LIPOPROTEIN LPPH protein.
ACCESSION   LT708304-3648
PROTEIN_ID  SIU02234.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="lppH"
                     /locus_tag="BQ2027_MB3607"
                     /note="Mb3607, lppH, len: 237 aa. Equivalent to Rv3576,
                     len: 237 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.6% identity in 237 aa overlap). Possible lppH,
                     conserved lipoprotein, similar in part with proteins from
                     Mycobacterium tuberculosis; C-terminus of
                     Q11053|PKNH_MYCTU|PKNH|Rv1266c|MT1304|MTCY50.16 PROBABLE
                     SERINE/THREONINE-PROTEIN KINASE (EC 2.7.1.-) (626 aa)
                     FASTA scores: opt: 396, E(): 6.5e-19, (36.0% identity in
                     200 aa overlap); and with P71740|LPPR|Rv2403c|MTCY253.17
                     PROBABLE LIPOPROTEIN PROTEIN (251 aa), FASTA scores: opt:
                     134, E(): 0.087, (22.7% identity in 207 aa overlap).
                     Contains PS00013 Prokaryotic membrane lipoprotein lipid
                     attachment site. Note that previously known as pknM.
                     Protein product from Mb3607 detected using shotgun mass
                     spectrometry and SWATH mass spectrometry. Mb3607 found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing (TPM > 20)."
                     /db_xref="InterPro:IPR026954"
                     /db_xref="InterPro:IPR038232"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y4L0"
BEGIN
        1 MGKQLAALAA LVGACMLAAG CTNVVDGTAV AADKSGPLHQ DPIPVSALEG LLLDLSQINA
       61 ALGATSMKVW FNAKAMWDWS KSVADKNCLA IDGPAQEKVY AGTGWTAMRG QRLDDSINDS
      121 KKRDHYAIQA VVGFPTAHDA EEFYSSSVQS WSSCSNRRFV EVTPGQDDAA WTVADVVNDN
      181 GMLSSSQVQE GGDGWTCQRA LTARNNVTID IVTCAYSQPD LVAIGIANQI AAKVAKQ
//