LOCUS       SIU02219.1               377 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            ACYL-COA DEHYDROGENASE FADE31 protein.
ACCESSION   LT708304-3633
PROTEIN_ID  SIU02219.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="fadE31"
                     /locus_tag="BQ2027_MB3592"
                     /note="Mb3592, fadE31, len: 377 aa. Equivalent to Rv3562,
                     len: 377 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 377 aa overlap). Probable fadE31,
                     acyl-CoA dehydrogenase (EC 1.3.99.-), similar to many e.g.
                     Q9RJX2|SCF37.29c from Streptomyces coelicolor (393 aa),
                     FASTA scores: opt: 657, E(): 1.7e-34, (36.45% identity in
                     351 aa overlap); Q9A5G9|CC2478 from Caulobacter crescentus
                     (407 aa), FASTA scores: opt: 653, E(): 3.2e-34, (33.95%
                     identity in 392 aa overlap); Q9EX72|MLHC from Rhodococcus
                     erythropolis (324 aa) FASTA scores: opt: 631, E():
                     6.5e-33, (36.95% identity in 330 aa overlap);
                     P45867|ACDA_BACSU|ACD from Bacillus subtilis (379 aa),
                     FASTA scores: opt: 347, E(): 1e-15, (28.6% identity in 385
                     aa overlap); etc. Also similar to other from Mycobacterium
                     tuberculosis e.g. P96842|FADE30|Rv3560c|MTCY06G11.07c (385
                     aa), FASTA scores: opt: 843, E(): 2.3e-46, (38.95%
                     identity in 380 aa overlap). COULD BELONG TO THE ACYL-COA
                     DEHYDROGENASES FAMILY. Protein product from Mb3592
                     detected using SWATH mass spectrometry."
                     /db_xref="GOA:A0A1R3Y4M5"
                     /db_xref="InterPro:IPR006091"
                     /db_xref="InterPro:IPR009075"
                     /db_xref="InterPro:IPR009100"
                     /db_xref="InterPro:IPR013786"
                     /db_xref="InterPro:IPR036250"
                     /db_xref="InterPro:IPR037069"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y4M5"
BEGIN
        1 MDLNFDDETL AFQAEVREFL AANAASIPTK SYDNAEGFAQ HRYWDRVLFD AGLSVITWPA
       61 KYGGRDAPLL HWIVFEEEYF RAGAPGRASA NGTSMLAPTL FAHGTAEQLD RILPKMASGE
      121 QIWAQAWSEP ESGSDLASLR STASKVDGGW LLNGQKIWSS RAPFADMGFG LFRSDPAVER
      181 HRGLTYFMFD LKAKGVTVRP IAQLGGDTGF GEIFLDDVFV PDRDVIGAPN DGWRAAMSTS
      241 SNERGMSLRS PARFLASAER LVQLWKDRGS PPEFADRVAD AWIKAQAYRL QTFGTVTRLA
      301 AGGELGAESS VTKVFWSELD VHLHQTALDL RGADGELAGP WTEGLLFALG GPIYAGTNEI
      361 QRNIIAERLL GLPREKT
//