LOCUS       SIU02201.1               339 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            ACYL-COA DEHYDROGENASE FADE28 protein.
ACCESSION   LT708304-3615
PROTEIN_ID  SIU02201.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="fadE28"
                     /locus_tag="BQ2027_MB3574C"
                     /note="Mb3574c, fadE28, len: 339 aa. Equivalent to
                     Rv3544c, len: 339 aa, from Mycobacterium tuberculosis
                     strain H37Rv, (100.0% identity in 339 aa overlap).
                     Probable fadE28, acyl-CoA dehydrogenase (EC 1.3.99.-),
                     similar to many e.g. Q9RJX3|SCF37.28c from Streptomyces
                     coelicolor (362 aa), FASTA scores: opt: 334, E(): 5.1e-13,
                     (27.65% identity in 329 aa overlap); Q9A5G8|CC2479 from
                     Caulobacter crescentus (344 aa), FASTA scores: opt: 278,
                     E(): 1.2e-09, (26.95% identity in 319 aa overlap);
                     O29813|AF0436 from Archaeoglobus fulgidus (382 aa) FASTA
                     scores: opt: 205, E(): 3.5e-05, (24.75% identity in 384 aa
                     overlap); etc. Also similar to other from Mycobacterium
                     tuberculosis e.g. O53550|FADE27|Rv3505|MTV023.12 (373 aa)
                     FASTA scores: opt: 497, E(): 7e-23, (30.3% identity in 343
                     aa overlap); and to
                     P46703|ACDP_MYCLE|FADE25|ACD|ML0737|B1308_F1_34 PROBABLE
                     ACYL-COA DEHYDROGENASE from Mycobacterium leprae (389 aa)
                     FASTA scores: opt: 165, E(): 0.0012, (25.2% identity in
                     345 aa overlap). COULD BELONG TO THE ACYL-COA
                     DEHYDROGENASES FAMILY. Mb3574c found to be expressed
                     during exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:A0A1R3Y4H3"
                     /db_xref="InterPro:IPR009075"
                     /db_xref="InterPro:IPR009100"
                     /db_xref="InterPro:IPR013786"
                     /db_xref="InterPro:IPR036250"
                     /db_xref="InterPro:IPR037069"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y4H3"
BEGIN
        1 MDFDPTAEQQ AVADVVTSVL ERDISWEALV CGGVTALPVP ERLGGDGVGL FEVGALLTEV
       61 GRHGAVTPAL ATLGLGVVPL LELASAEQQD RFLAGVAKGG VLTAALNEPG AALPDRPATS
      121 FVGGRLSGTK VGVGYAEQAD WMLVTADNAV VVVSPTADGV RMVRTPTSNG SDEYVMTMDG
      181 VAVADCDILA DVAAHRVNQL ALAVMGAYAD GLVAGALRLT ADYVANRKQF GKPLSTFQTV
      241 AAQLAEVYIA SRTIDLVAKS VIWRLAEDLD AGDDLGVLGY WVTSQAPPAM QICHHLHGGM
      301 GMDVTYPMHR YYSTIKDLTR LLGGPSHRLE LLGARCSLT
//