LOCUS SIU02198.1 129 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 Enoyl coenzyme A hydratase IgrE protein. ACCESSION LT708304-3612 PROTEIN_ID SIU02198.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB3571C" /note="Mb3571c, -, len: 129 aa. Equivalent to Rv3541c, len: 129 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 129 aa overlap). Hypothetical protein, showing some similarity to Q9CBJ7|ML1909 HYPOTHETICAL PROTEIN from Mycobacterium leprae (142 aa) FASTA scores: opt: 110, E(): 1.2, (27.95% identity in 118 aa overlap); and other (see also BLASTP results) e.g. Q9L0M3|SCD82.08 HYPOTHETICAL 15.2 KDA PROTEIN from Streptomyces coelicolor (142 aa), FASTA scores: opt: 127, E(): 0.086, (27.65% identity in 123 aa overlap). Contains PS00075 Dihydrofolate reductase signature. Protein product from Mb3571c detected using SWATH mass spectrometry. Mb3571c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing (TPM > 20)." /db_xref="InterPro:IPR029069" /db_xref="UniProtKB/TrEMBL:A0A1R3Y4K7" /experiment="experimental evidence, no additional details recorded" BEGIN 1 MTVVGAVLPE LKLYGDPTFI VSTALATRDF QDVHHDRDKA VAQGSKDIFV NILTDTGLVQ 61 RYVTDWAGPS ALIKSIGLRL GVPWYAYDTV TFSGEVTAVN DGLITVKVVG RNTLGDHVTA 121 TVELSMRDS //