LOCUS       SIU02189.1               406 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 ppe
            family protein ppe61 protein.
ACCESSION   LT708304-3603
PROTEIN_ID  SIU02189.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="PPE61"
                     /locus_tag="BQ2027_MB3562"
                     /note="Mb3562, PPE61, len: 406 aa. Equivalent to Rv3532,
                     len: 406 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 406 aa overlap). Member of the
                     Mycobacterium tuberculosis PPE protein family, similar to
                     many, e.g. O53956|Rv1807|MTV049.29 (403 aa), FASTA scores:
                     opt: 954, E(): 1.1e-43, (44.1% identity in 417 aa
                     overlap),Mb3562 found to be expressed during exponential
                     growth in Sauton's minimal media by RNA-sequencing (TPM >
                     20)."
                     /db_xref="InterPro:IPR000030"
                     /db_xref="InterPro:IPR022171"
                     /db_xref="InterPro:IPR038332"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y4I7"
BEGIN
        1 MFMDFAMLPP EVNSTRMYSG PGAGSLWAAA AAWDQVSAEL QSAAETYRSV IASLTGWQWL
       61 GPSSVRMGAA VTPYVEWLTT TAAQARQTAT QITAAATGFE QAFAMTVPPP AIMANRAQVL
      121 SLIATNFFGQ NTAAIAALET QYAEMWEQDA TAMYDYAATS AAARTLTPFT SPQQDTNSAG
      181 LPAQSAEVSR ATANAGAADG NWLGNLLEEI GILLLPIAPE LTPFFLEAGE IVNAIPFPSI
      241 VGDEFCLLDG LLAWYATIGS INNINSMGTG IIGAEKNLGI LPELGSAAAA AAPPPADIAP
      301 AFLAPLTSMA KSLSDGALRG PGEVSAAMRG AGTIGQMSVP PAWKAPAVTT VRAFDATPMT
      361 TLPGGDAPAA GVPGLPGMPA SGAGRAGVVP RYGVRLTVMT RPLSGG
//