LOCUS SIU02189.1 406 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 ppe family protein ppe61 protein. ACCESSION LT708304-3603 PROTEIN_ID SIU02189.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="PPE61" /locus_tag="BQ2027_MB3562" /note="Mb3562, PPE61, len: 406 aa. Equivalent to Rv3532, len: 406 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 406 aa overlap). Member of the Mycobacterium tuberculosis PPE protein family, similar to many, e.g. O53956|Rv1807|MTV049.29 (403 aa), FASTA scores: opt: 954, E(): 1.1e-43, (44.1% identity in 417 aa overlap),Mb3562 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing (TPM > 20)." /db_xref="InterPro:IPR000030" /db_xref="InterPro:IPR022171" /db_xref="InterPro:IPR038332" /db_xref="UniProtKB/TrEMBL:A0A1R3Y4I7" BEGIN 1 MFMDFAMLPP EVNSTRMYSG PGAGSLWAAA AAWDQVSAEL QSAAETYRSV IASLTGWQWL 61 GPSSVRMGAA VTPYVEWLTT TAAQARQTAT QITAAATGFE QAFAMTVPPP AIMANRAQVL 121 SLIATNFFGQ NTAAIAALET QYAEMWEQDA TAMYDYAATS AAARTLTPFT SPQQDTNSAG 181 LPAQSAEVSR ATANAGAADG NWLGNLLEEI GILLLPIAPE LTPFFLEAGE IVNAIPFPSI 241 VGDEFCLLDG LLAWYATIGS INNINSMGTG IIGAEKNLGI LPELGSAAAA AAPPPADIAP 301 AFLAPLTSMA KSLSDGALRG PGEVSAAMRG AGTIGQMSVP PAWKAPAVTT VRAFDATPMT 361 TLPGGDAPAA GVPGLPGMPA SGAGRAGVVP RYGVRLTVMT RPLSGG //