LOCUS       SIU02119.1                73 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            TRANSLATION INITIATION FACTOR IF-1 INFA protein.
ACCESSION   LT708304-3533
PROTEIN_ID  SIU02119.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="infA"
                     /locus_tag="BQ2027_MB3491C"
                     /note="Mb3491c, infA, len: 73 aa. Equivalent to Rv3462c,
                     len: 73 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 73 aa overlap). Probable infA,
                     initiation factor IF-1, equivalent to P45957|ML1962|INFA
                     TRANSLATION INITIATION FACTOR IF-1 from Mycobacterium
                     bovis (72 aa) and Mycobacterium leprae (72 aa), FASTA
                     scores: opt: 472, E(): 6.6e-28, (100.0% identity in 72 aa
                     overlap). Also highly similar to others e.g.
                     O54209|IF1_STRCO|INFA|SC6G4.03 from Streptomyces
                     coelicolor (73 aa), FASTA scores: opt: 424, E(): 2e-24,
                     (84.95% identity in 73 aa overlap);
                     O50630|IF1_BACHD|INFA|BH0158 from Bacillus halodurans (71
                     aa), FASTA scores: opt: 388, E(): 8.1e-22, (77.8% identity
                     in 72 aa overlap); Q9XD14|IF1_LEPIN|INFA from Leptospira
                     interrogans (71 aa), FASTA scores: opt: 376, E(): 6e-21,
                     (80.0% identity in 70 aa overlap); etc. CONTAINS 1 'S1
                     MOTIF' DOMAIN. BELONGS TO THE IF-1 FAMILY. Protein product
                     from Mb3491c detected using shotgun mass spectrometry and
                     SWATH mass spectrometry. Mb3491c found to be expressed
                     during exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:P0A5H6"
                     /db_xref="InterPro:IPR004368"
                     /db_xref="InterPro:IPR006196"
                     /db_xref="InterPro:IPR012340"
                     /db_xref="UniProtKB/Swiss-Prot:P0A5H6"
BEGIN
        1 MAKKDGAIEV EGRVVEPLPN AMFRIELENG HKVLAHISGK MRQHYIRILP EDRVVVELSP
       61 YDLSRGRIVY RYK
//