LOCUS       SIU02103.1               105 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 ESAT-
            6 like protein EsxU protein.
ACCESSION   LT708304-3517
PROTEIN_ID  SIU02103.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="esxU"
                     /locus_tag="BQ2027_MB3475C"
                     /note="Mb3475c, len: 105 aa. Equivalent to Rv3445c len:
                     105 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 105 aa overlap). EsxU, ESAT-6 like
                     protein (see citations below), showing weak similarity to
                     O30373|VCD|PA2257 pyoverdine biosynthesis protein from
                     Pseudomonas aeruginosa (215 aa), FASTA scores: opt:
                     103,E(): 5.6, (32.35% identity in 133 aa overlap). Seems
                     to belong to the ESAT6 family. Start changed since first
                     submission (-20 aa). Mb3475c found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="InterPro:IPR010310"
                     /db_xref="InterPro:IPR036689"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y467"
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MSTPNTLNAD FDLMRSVAGI TDARNEEIRA MLQAFIGRMS GVPPSVWGGL AAARFQDVVD
       61 RWNAESTRLY HVLHAIADTI RHNEAALREA GQIHARHIAA AGGDL
//