LOCUS       SIU02080.1               100 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 10
            KDA CHAPERONIN GROES (PROTEIN CPN10) (PROTEIN GROES) (
            BCG-A HEAT SHOCK PROTEIN) (10 KDA ANTIGEN) protein.
ACCESSION   LT708304-3494
PROTEIN_ID  SIU02080.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="groES"
                     /locus_tag="BQ2027_MB3452C"
                     /standard_name="cpn10; mpt57"
                     /note="Mb3452c, groES, len: 100 aa. Equivalent to Rv3418c,
                     len: 100 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 100 aa overlap). groES (alternate gene
                     names: cpn10, mpt57), 10 kDa chaperonin (protein cpn10)
                     (see citations below), equivalent to
                     P24301|CH10_MYCLE|MOPB|GROES|CHPA|ML0380|B1620_C3_227|B229
                     _C3_247 from Mycobacterium leprae (99 aa), FASTA scores:
                     opt: 568, E(): 2.1e-31, (89.9% identity in 99 aa overlap).
                     And also strongly identical to others e.g.
                     O86017|CH10_MYCAV|MOPB|GROES from Mycobacterium avium and
                     Mycobacterium paratuberculosis (99 aa), FASTA scores: opt:
                     611, E(): 2.9e-34, (96.95% identity in 99 aa overlap);
                     P15020|CH10_MYCBO|MOPB|GROES from Mycobacterium bovis (99
                     aa), FASTA scores: opt: 596, E(): 2.9e-33, (98.95%
                     identity in 94 aa overlap);
                     P40172|CH10_STRCO|GROES|SC6G4.39 from Streptomyces
                     coelicolor and Streptomyces lividans (102 aa), FASTA
                     scores: opt: 480, E(): 1.6e-25, (76.75% identity in 99 aa
                     overlap); etc. Also identical to MSG10KAG_1, MT10KAG_1,
                     MTBCGA_1. Contains PS00681 Chaperonins cpn10 signature.
                     BELONGS TO THE GROES CHAPERONIN FAMILY. Protein product
                     from Mb3452c detected using shotgun mass spectrometry and
                     SWATH mass spectrometry. Mb3452c found to be expressed
                     during exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:P15020"
                     /db_xref="InterPro:IPR011032"
                     /db_xref="InterPro:IPR018369"
                     /db_xref="InterPro:IPR020818"
                     /db_xref="InterPro:IPR037124"
                     /db_xref="UniProtKB/Swiss-Prot:P15020"
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MAKVNIKPLE DKILVQANEA ETTTASGLVI PDTAKEKPQE GTVVAVGPGR WDEDGEKRIP
       61 LDVAEGDTVI YSKYGGTEIK YNGEEYLILS ARDVLAVVSK
//