LOCUS       SIU02043.1               329 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            LYTB-RELATED PROTEIN LYTB1 protein.
ACCESSION   LT708304-3457
PROTEIN_ID  SIU02043.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="lytB1"
                     /locus_tag="BQ2027_MB3414C"
                     /note="Mb3414c, lytB1, len: 329 aa. Equivalent to Rv3382c,
                     len: 329 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 329 aa overlap). Probable lytB1,
                     lytB-related protein, highly similar to many e.g.
                     Q9HVM7|LYTB_PSEAE|PA4557 from Pseudomonas aeruginosa (314
                     aa), FASTA scores: opt: 1048, E(): 2e-55, (53.2% identity
                     in 314 aa overlap); Q9JR39|LYTB|NMA0624|NMB1831 from
                     Neisseria meningitidis (serogroup A and B) (322 aa), FASTA
                     scores: opt: 1041, E(): 5.4e-55, (52.25% identity in 312
                     aa overlap); P22565|LYTB_ECOLI|B0029 from Escherichia coli
                     strain K12 (316 aa), FASTA scores: opt: 1013, E():
                     2.5e-53, (51.45% identity in 311 aa overlap) (for more
                     information about lytB protein, see citation below);
                     Q9X781|LYTB_MYCLE|LYTB2|ML1938|MLCB1222.06c from
                     Mycobacterium leprae (332 aa), FASTA scores: opt: 979,
                     E(): 2.8e-51, (51.3% identity in 312 aa overlap); etc.
                     Also similar to Q9PAS9|XF2416 DRUG TOLERANCE PROTEIN from
                     Xylella fastidiosa (316 aa), FASTA scores: opt: 1043, E():
                     4.1e-55, (53.65% identity in 315 aa overlap). And similar
                     to O53458|Rv1110|LYTB2|MTV017.63 from Mycobacterium
                     tuberculosis (335 aa), FASTA scores: opt: 975, E():
                     4.9e-51, (51.3% identity in 312 aa overlap). BELONGS TO
                     THE LYTB FAMILY. Mb3414c found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:P0A5I3"
                     /db_xref="InterPro:IPR003451"
                     /db_xref="UniProtKB/Swiss-Prot:P0A5I3"
BEGIN
        1 MAEVFVGPVA QGYASGEVTV LLASPRSFCA GVERAIETVK RVLDVAEGPV YVRKQIVHNT
       61 VVVAELRDRG AVFVEDLDEI PDPPPPGAVV VFSAHGVSPA VRAGADERGL QVVDATCPLV
      121 AKVHAEAARF AARGDTVVFI GHAGHEETEG TLGVAPRSTL LVQTPADVAA LNLPEGTQLS
      181 YLTQTTLALD ETADVIDALR ARFPTLGQPP SEDICYATTN RQRALQSMVG ECDVVLVIGS
      241 CNSSNSRRLV ELAQRSGTPA YLIDGPDDIE PEWLSSVSTI GVTAGASAPP RLVGQVIDAL
      301 RGYASITVVE RSIATETVRF GLPKQVRAQ
//