LOCUS       SIU02032.1               214 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE
            OXIDOREDUCTASE protein.
ACCESSION   LT708304-3446
PROTEIN_ID  SIU02032.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB3403C"
                     /note="Mb3403c, -, len: 214 aa. Equivalent to Rv3368c,
                     len: 214 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 214 aa overlap). Possible
                     oxidoreductase (EC 1.-.-.-), equivalent to
                     O07697|MLCL383.23|ML0418 HYPOTHETICAL 23.6 KDA PROTEIN
                     (PUTATIVE OXIDOREDUCTASE) from Mycobacterium leprae (210
                     aa), FASTA scores: opt: 1215, E(): 1.5e-74, (81.4%
                     identity in 210 aa overlap). Also similar to O30106|AF0131
                     PUTATIVE NAD(P)H-FLAVIN OXIDOREDUCTASE from Archaeoglobus
                     fulgidus (194 aa), FASTA scores: opt: 139, E(): 0.028,
                     (29.0% identity in 207 aa overlap); Q60049|NOX_THETH NADH
                     DEHYDROGENASE from Thermus aquaticus (subsp. thermophilus)
                     (205 aa), FASTA scores: opt: 169, E(): 0.00028, (28.3%
                     identity in 212 aa overlap); and shows some similarity to
                     other hypothetical proteins (unknowns or oxidoreductases).
                     Protein product from Mb3403c detected using shotgun mass
                     spectrometry. Mb3403c found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:A0A1R3Y406"
                     /db_xref="InterPro:IPR000415"
                     /db_xref="InterPro:IPR029479"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y406"
BEGIN
        1 MTLNLSVDEV LTTTRSVRKR LDFDKPVPRD VLMECLELAL QAPTGSNSQG WQWVFVEDAA
       61 KKKAIADVYL ANARGYLSGP APEYPDGDTR GERMGRVRDS ATYLAEHMHR APVLLIPCLK
      121 GREDESAVGG VSFWASLFPA VWSFCLALRS RGLGSCWTTL HLLDNGEHKV ADVLGIPYDE
      181 YSQGGLLPIA YTQGIDFRPA KRLPAESVTH WNGW
//