LOCUS SIU02032.1 214 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE OXIDOREDUCTASE protein. ACCESSION LT708304-3446 PROTEIN_ID SIU02032.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB3403C" /note="Mb3403c, -, len: 214 aa. Equivalent to Rv3368c, len: 214 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 214 aa overlap). Possible oxidoreductase (EC 1.-.-.-), equivalent to O07697|MLCL383.23|ML0418 HYPOTHETICAL 23.6 KDA PROTEIN (PUTATIVE OXIDOREDUCTASE) from Mycobacterium leprae (210 aa), FASTA scores: opt: 1215, E(): 1.5e-74, (81.4% identity in 210 aa overlap). Also similar to O30106|AF0131 PUTATIVE NAD(P)H-FLAVIN OXIDOREDUCTASE from Archaeoglobus fulgidus (194 aa), FASTA scores: opt: 139, E(): 0.028, (29.0% identity in 207 aa overlap); Q60049|NOX_THETH NADH DEHYDROGENASE from Thermus aquaticus (subsp. thermophilus) (205 aa), FASTA scores: opt: 169, E(): 0.00028, (28.3% identity in 212 aa overlap); and shows some similarity to other hypothetical proteins (unknowns or oxidoreductases). Protein product from Mb3403c detected using shotgun mass spectrometry. Mb3403c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:A0A1R3Y406" /db_xref="InterPro:IPR000415" /db_xref="InterPro:IPR029479" /db_xref="UniProtKB/TrEMBL:A0A1R3Y406" BEGIN 1 MTLNLSVDEV LTTTRSVRKR LDFDKPVPRD VLMECLELAL QAPTGSNSQG WQWVFVEDAA 61 KKKAIADVYL ANARGYLSGP APEYPDGDTR GERMGRVRDS ATYLAEHMHR APVLLIPCLK 121 GREDESAVGG VSFWASLFPA VWSFCLALRS RGLGSCWTTL HLLDNGEHKV ADVLGIPYDE 181 YSQGGLLPIA YTQGIDFRPA KRLPAESVTH WNGW //