LOCUS       SIU02023.1               396 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE
            OXIDOREDUCTASE protein.
ACCESSION   LT708304-3437
PROTEIN_ID  SIU02023.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB3394"
                     /note="Mb3394, -, len: 396 aa. Equivalent to Rv3359, len:
                     396 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 396 aa overlap). Possible
                     oxidoreductase (EC 1.-.-.-), similar to N-terminal part of
                     various proteins (hypothetical unknowns or
                     oxidoreductases) e.g. Q9ZB94 HYPOTHETICAL 69.3 KDA PROTEIN
                     from Rhodococcus erythropolis (649 aa), FASTA scores: opt:
                     509, E(): 3e-24, (30.0% identity in 380 aa overlap);
                     O29991|AF0248 NADH-DEPENDENT FLAVIN OXIDOREDUCTASE from
                     Archaeoglobus fulgidus (378 aa), FASTA scores: opt: 478,
                     E(): 1.6e-22, (32.45% identity in 379 aa overlap);
                     Q9HUH9|PA4986 PROBABLE OXIDOREDUCTASE from Pseudomonas
                     aeruginosa (648 aa), FASTA scores: opt: 412, E(): 3.3e-18,
                     (30.45% identity in 384 aa overlap); Q9KCT8|BH1481 NADH
                     OXIDASE from Bacillus halodurans (338 aa), FASTA scores:
                     opt: 404, E(): 6.1e-18, (30.2% identity in 275 aa
                     overlap); etc. Some weak similarity to Mycobacterium
                     leprae MLCB1779_10. Protein product from Mb3394 detected
                     using SWATH mass spectrometry. Mb3394 found to be
                     expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /db_xref="GOA:A0A1R3Y3Z9"
                     /db_xref="InterPro:IPR001155"
                     /db_xref="InterPro:IPR013785"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y3Z9"
BEGIN
        1 MAPGSCEAPD VFNPAKLGPL TLRNRVIKAA TFEARTPDAL VTDDLIEYHR LPAAGGVAMT
       61 TVAYCAVSPG GRTGGNQIWM RPHAVPGLRR LTEAIHAEGA AISAQIGHAG PVADARSNQA
      121 TALAPVRFFN PIAMRFAQKA TREDIDDVLA AHAHAARLAV DAGFDAVEIH LGHNYLASAF
      181 LSPLLNRRDD EFGGSLQNRA KVARGLVMAV RRAVRQQVAV TAKLNMTDGI RGGITVDEAL
      241 TTARWLQDDG GLDAIELTAG SSLVNPMYLF RGDAPVKEFA AAFKPPLRWG IRMTGHRFFR
      301 EYPYRDAYLL REARLFRAEL TIPLILLGGI TNRTTMDLAM AEGFEFVAMA RALLAEPDLV
      361 NRIAAEGSQV RSACTHCNQC MATIYRRTHC VVTGAP
//