LOCUS SIU02023.1 396 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE OXIDOREDUCTASE protein. ACCESSION LT708304-3437 PROTEIN_ID SIU02023.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB3394" /note="Mb3394, -, len: 396 aa. Equivalent to Rv3359, len: 396 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 396 aa overlap). Possible oxidoreductase (EC 1.-.-.-), similar to N-terminal part of various proteins (hypothetical unknowns or oxidoreductases) e.g. Q9ZB94 HYPOTHETICAL 69.3 KDA PROTEIN from Rhodococcus erythropolis (649 aa), FASTA scores: opt: 509, E(): 3e-24, (30.0% identity in 380 aa overlap); O29991|AF0248 NADH-DEPENDENT FLAVIN OXIDOREDUCTASE from Archaeoglobus fulgidus (378 aa), FASTA scores: opt: 478, E(): 1.6e-22, (32.45% identity in 379 aa overlap); Q9HUH9|PA4986 PROBABLE OXIDOREDUCTASE from Pseudomonas aeruginosa (648 aa), FASTA scores: opt: 412, E(): 3.3e-18, (30.45% identity in 384 aa overlap); Q9KCT8|BH1481 NADH OXIDASE from Bacillus halodurans (338 aa), FASTA scores: opt: 404, E(): 6.1e-18, (30.2% identity in 275 aa overlap); etc. Some weak similarity to Mycobacterium leprae MLCB1779_10. Protein product from Mb3394 detected using SWATH mass spectrometry. Mb3394 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:A0A1R3Y3Z9" /db_xref="InterPro:IPR001155" /db_xref="InterPro:IPR013785" /db_xref="UniProtKB/TrEMBL:A0A1R3Y3Z9" BEGIN 1 MAPGSCEAPD VFNPAKLGPL TLRNRVIKAA TFEARTPDAL VTDDLIEYHR LPAAGGVAMT 61 TVAYCAVSPG GRTGGNQIWM RPHAVPGLRR LTEAIHAEGA AISAQIGHAG PVADARSNQA 121 TALAPVRFFN PIAMRFAQKA TREDIDDVLA AHAHAARLAV DAGFDAVEIH LGHNYLASAF 181 LSPLLNRRDD EFGGSLQNRA KVARGLVMAV RRAVRQQVAV TAKLNMTDGI RGGITVDEAL 241 TTARWLQDDG GLDAIELTAG SSLVNPMYLF RGDAPVKEFA AAFKPPLRWG IRMTGHRFFR 301 EYPYRDAYLL REARLFRAEL TIPLILLGGI TNRTTMDLAM AEGFEFVAMA RALLAEPDLV 361 NRIAAEGSQV RSACTHCNQC MATIYRRTHC VVTGAP //