LOCUS       SIU02016.1               123 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE
            OXIDOREDUCTASE protein.
ACCESSION   LT708304-3430
PROTEIN_ID  SIU02016.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB3387C"
                     /note="Mb3387c, -, len: 123 aa. Equivalent to Rv3352c,
                     len: 123 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 123 aa overlap). Possible
                     oxidoreductase (EC 1.-.-.-), similar to part of several
                     oxidoreductases (and hypothetical proteins) from diverse
                     organisms e.g. Q9KYD6|SCD72A.20 PUTATIVE LIPOPROTEIN
                     (FRAGMENT) from Streptomyces coelicolor (403 aa), FASTA
                     scores: opt: 348, E(): 7.9e-15, (51.0% identity in 102 aa
                     overlap); BAB53081|MLR6875 PROBABLE OXIDOREDUCTASE from
                     Rhizobium loti (Mesorhizobium loti) (479 aa), FASTA
                     scores: opt: 262, E(): 2.3e-09, (53.85% identity in 78 aa
                     overlap); O94206|OX1 OXIDOREDUCTASE from Claviceps
                     purpurea (Ergot fungus) (483 aa), FASTA scores: opt: 245,
                     E(): 2.7e-08, (42.6% identity in 115 aa overlap);
                     Q9KHK2|ENCM PUTATIVE FAD-DEPENDENT OXYGENASE ENCM from
                     Streptomyces maritimus (464 aa), FASTA scores: opt: 238,
                     E(): 7.2e-08, (43.95% identity in 91 aa overlap); etc.
                     Also highly similar to part of O53608|Rv0063|MTV030.06
                     OXIDOREDUCTASE (479 aa), FASTA scores: opt: 599, E():
                     1.6e-30, (71.55% identity in 123 aa overlap); and to other
                     Mycobacterium tuberculosis proteins e.g. Rv3353c and
                     Rv3351c. All show similarity to a family of
                     oxidoreductases in M. tuberculosis, suggesting that
                     frameshift mutations may have occurred. Sequence has been
                     checked but no errors were found."
                     /db_xref="GOA:A0A1R3Y4P0"
                     /db_xref="InterPro:IPR006094"
                     /db_xref="InterPro:IPR016166"
                     /db_xref="InterPro:IPR036318"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y4P0"
BEGIN
        1 MSAATDLYAV HQALAGESRA IPTGSCPTVG VAGLTLGGGL GADSRHAGLT CDALKSATVV
       61 LPGGDAVSAS ADDHAELFWA LRGGGGGNFG VTTSMTFARF PTADCDVVRV DFAPSAAAQV
      121 LVG
//