LOCUS       SIU01981.1               221 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            MOAD-MOAE FUSION PROTEIN MOAX protein.
ACCESSION   LT708304-3395
PROTEIN_ID  SIU01981.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="moaX"
                     /locus_tag="BQ2027_MB3352C"
                     /note="Mb3352c, moaX, len: 221 aa. Equivalent to Rv3323c,
                     len: 221 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 221 aa overlap). Probable moaX,
                     MoaD-MoaE fusion protein, similar (whole or partial) to
                     several MoaD and MoaE proteins e.g. Q9RR88|DR2607
                     MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN D/E from
                     Deinococcus radiodurans (229 aa), FASTA scores: opt: 407,
                     E(): 1.8e-18, (32.75% identity in 223 aa overlap);
                     Q9K8I7|MOAE|BH3019 MOLYBDOPTERIN CONVERTING FACTOR
                     (SUBUNIT 2) from Bacillus halodurans (156 aa), FASTA
                     scores: opt: 375, E(): 1.3e-16, (41.65% identity in 132 aa
                     overlap); O31705|MOAE MOLYBDOPTERIN CONVERTING FACTOR
                     (SUBUNIT 2) from Bacillus subtilis (157 aa), FASTA scores:
                     opt: 368, E(): 3.6e-16, (41.65% identity in 132 aa
                     overlap); etc. C-terminus highly similar to
                     O05795|MOAE_MYCTU|Rv3119|MT3201|MTCY164.29|MOAE1 PUTATIVE
                     MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN E from
                     Mycobacterium tuberculosis (147 aa), FASTA scores: opt:
                     733, E(): 5.4e-39, (76.2% identity in 143 aa overlap); and
                     N-terminus highly similar to
                     O05789|MOAD1|Rv3112|MTCY164.22 PUTATIVE MOLYBDENUM
                     COFACTOR BIOSYNTHESIS PROTEIN D from Mycobacterium
                     tuberculosis (83 aa), FASTA scores: opt: 333, E():
                     3.2e-14, (65.05% identity in 83 aa overlap). Protein
                     product from Mb3352c detected using shotgun mass
                     spectrometry and SWATH mass spectrometry. Mb3352c found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing (TPM > 20)."
                     /db_xref="GOA:A0A1R3Y3S9"
                     /db_xref="InterPro:IPR003448"
                     /db_xref="InterPro:IPR003749"
                     /db_xref="InterPro:IPR012675"
                     /db_xref="InterPro:IPR016155"
                     /db_xref="InterPro:IPR036563"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y3S9"
BEGIN
        1 MITVNVLYFG AVREACKVAH EKISLESGTT VDGLVDQLQI DYPPLADFRK RVRMAVNESI
       61 APASTILDDG DTVAFIPQVA GGSDVYCRLT DEPLSVDEVL NAISGPSQGG AVIFVGTVRN
      121 NNNGHEVTKL YYEAYPAMVH RTLMDIIEEC ERQADGVRVA VAHRTGELRI GDAAVVIGAS
      181 APHRAAAFDA ARMCIERLKQ DVPIWKKEFA LDGVEWVANR P
//