LOCUS       SIU01967.1               299 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 acid
            phosphatase (acid phosphomonoesterase) (phosphomonoesterase)
            (glycerophosphatase) protein.
ACCESSION   LT708304-3381
PROTEIN_ID  SIU01967.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="sapm"
                     /locus_tag="BQ2027_MB3338"
                     /note="Mb3338, -, len: 299 aa. Equivalent to Rv3310, len:
                     299 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.7% identity in 299 aa overlap). Possible acid
                     phosphatase (EC 3.1.3.2), similar to several fungal or
                     bacterial acid phosphatases e.g. BAB50846|MLR4110 from
                     Rhizobium loti (Mesorhizobium loti) (292 aa), FASTA
                     scores: opt: 460, E(): 4.8e-22, (38.65% identity in 295 aa
                     overlap); P34724|PHOA_ASPNG from Aspergillus niger (417
                     aa), FASTA scores: opt: 172, E(): 0.0013, (29.1% identity
                     in 306 aa overlap); P08540|PHOX_KLULA from Kluyveromyces
                     lactis (Yeast) (421 aa), FASTA scores: opt: 170, E():
                     0.0018, (27.8% identity in 266 aa overlap);
                     P37274|PHOA_PENCH from Penicillium chrysogenum (412 aa),
                     FASTA scores: opt: 163, E(): 0.0049, (29.05% identity in
                     303 aa overlap); etc. Protein product from Mb3338 detected
                     using SWATH mass spectrometry. Mb3338 found to be
                     expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /db_xref="GOA:A0A1R3Y3V0"
                     /db_xref="InterPro:IPR007312"
                     /db_xref="InterPro:IPR017850"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y3V0"
BEGIN
        1 MLRGIQALSR PLTRVYRALA VIGVLAASLL ASWVGAVPQV GLAASALPTF AHVVIVVEEN
       61 RSQAAIIGNK SAPFINSLAA NGAMMAQAFA ETHPSEPNYL ALFAGNTFGL TKNTCPVNGG
      121 ALPNLGSELL SAGYTFMGFA EDLPAVGSTV CSAGKYARKH VPWVNFSNVP ATLSVPFSAF
      181 PKPQNYPGLP TVSFVIPNAD NDMHDGSIAQ GDAWLNRHLS AYANWAKTNN SLLVVTWDED
      241 DGSSRNQIPT VFYGAHVRPG TYNETISHYN VLSTLEQIYG LPKTGYATNA PPITDIWGD
//