LOCUS SIU01967.1 299 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 acid phosphatase (acid phosphomonoesterase) (phosphomonoesterase) (glycerophosphatase) protein. ACCESSION LT708304-3381 PROTEIN_ID SIU01967.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="sapm" /locus_tag="BQ2027_MB3338" /note="Mb3338, -, len: 299 aa. Equivalent to Rv3310, len: 299 aa, from Mycobacterium tuberculosis strain H37Rv, (99.7% identity in 299 aa overlap). Possible acid phosphatase (EC 3.1.3.2), similar to several fungal or bacterial acid phosphatases e.g. BAB50846|MLR4110 from Rhizobium loti (Mesorhizobium loti) (292 aa), FASTA scores: opt: 460, E(): 4.8e-22, (38.65% identity in 295 aa overlap); P34724|PHOA_ASPNG from Aspergillus niger (417 aa), FASTA scores: opt: 172, E(): 0.0013, (29.1% identity in 306 aa overlap); P08540|PHOX_KLULA from Kluyveromyces lactis (Yeast) (421 aa), FASTA scores: opt: 170, E(): 0.0018, (27.8% identity in 266 aa overlap); P37274|PHOA_PENCH from Penicillium chrysogenum (412 aa), FASTA scores: opt: 163, E(): 0.0049, (29.05% identity in 303 aa overlap); etc. Protein product from Mb3338 detected using SWATH mass spectrometry. Mb3338 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:A0A1R3Y3V0" /db_xref="InterPro:IPR007312" /db_xref="InterPro:IPR017850" /db_xref="UniProtKB/TrEMBL:A0A1R3Y3V0" BEGIN 1 MLRGIQALSR PLTRVYRALA VIGVLAASLL ASWVGAVPQV GLAASALPTF AHVVIVVEEN 61 RSQAAIIGNK SAPFINSLAA NGAMMAQAFA ETHPSEPNYL ALFAGNTFGL TKNTCPVNGG 121 ALPNLGSELL SAGYTFMGFA EDLPAVGSTV CSAGKYARKH VPWVNFSNVP ATLSVPFSAF 181 PKPQNYPGLP TVSFVIPNAD NDMHDGSIAQ GDAWLNRHLS AYANWAKTNN SLLVVTWDED 241 DGSSRNQIPT VFYGAHVRPG TYNETISHYN VLSTLEQIYG LPKTGYATNA PPITDIWGD //