LOCUS       SIU01963.1               394 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 probable
            amidohydrolase amib1 (aminohydrolase) protein.
ACCESSION   LT708304-3377
PROTEIN_ID  SIU01963.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="amiB1"
                     /locus_tag="BQ2027_MB3334C"
                     /standard_name="amiB"
                     /note="Mb3334c, amiB1, len: 394 aa. Equivalent to Rv3306c,
                     len: 394 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 394 aa overlap). Probable amiB1,
                     aminohydrolase (EC 3.5.1.-), similar to several belonging
                     to peptidase family M40 (and to hypothetical proteins)
                     e.g. P54983|AMHX_BACSU AMIDOHYDROLASE AMHX from Bacillus
                     subtilis (EC 3.5.1.-) (389 aa), FASTA scores: opt: 286,
                     E(): 9.9e-10, (26.6% identity in 351 aa overlap);
                     P76052|ABGB_ECOLI Aminobenzoyl-glutamate utilizatio from
                     Escherichia coli (481 aa), FASTA scores: opt: 383, E():
                     2.1e-15, (30.5% identity in 328 aa overlap);
                     P44765|YDAJ_HAEIN HYPOTHETICAL PROTEIN HI0584 from
                     Haemophilus influenzae (423 aa), FASTA scores: opt: 297,
                     E(): 2.4e-10, (29.6% identity in 274 aa overlap). Note
                     that previously known as amiB. Protein product from
                     Mb3334c detected using SWATH mass spectrometry. Mb3334c
                     found to be expressed during exponential growth in
                     Sauton's minimal media by RNA-sequencing (TPM > 20)."
                     /db_xref="GOA:A0A1R3Y3S2"
                     /db_xref="InterPro:IPR002933"
                     /db_xref="InterPro:IPR011650"
                     /db_xref="InterPro:IPR017144"
                     /db_xref="InterPro:IPR017439"
                     /db_xref="InterPro:IPR036264"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y3S2"
BEGIN
        1 MPAASASDRV EELVRRRGGE LVELSHAIHA EPELAFAEHR SCAKAQALVA ERGFEITTAA
       61 GGLDTAFRAD YGSGPLVVGV CAEYDALPGI GHACGHNIIA ASAVGTALAL AEVADDLGLT
      121 VALLGTPAEE SGGGKALMLQ AGTFDDVAVA VMVHPGPTDI AGARSLALSE VTVRYRGKES
      181 HAAVAPHLGV NAADAVTVAQ VAIGVLRQQL APGQMVHGIV TDGGQAVNVI PGQARLQYAM
      241 RAVESDSLRE LQTRMFACFA AGALAAGCEY EIDEAAPAYA ELKPDPWLAD VCREEMQRLG
      301 REPLLPALEA ELPLGSTDMG NVTQVLPGIH PVIGLDAGAA TVHQRAFTVA SAGASADRAV
      361 VDGAIMLART VVRLAQTPDE RDRVLAAQQR RAAR
//