LOCUS SIU01963.1 394 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 probable amidohydrolase amib1 (aminohydrolase) protein. ACCESSION LT708304-3377 PROTEIN_ID SIU01963.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="amiB1" /locus_tag="BQ2027_MB3334C" /standard_name="amiB" /note="Mb3334c, amiB1, len: 394 aa. Equivalent to Rv3306c, len: 394 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 394 aa overlap). Probable amiB1, aminohydrolase (EC 3.5.1.-), similar to several belonging to peptidase family M40 (and to hypothetical proteins) e.g. P54983|AMHX_BACSU AMIDOHYDROLASE AMHX from Bacillus subtilis (EC 3.5.1.-) (389 aa), FASTA scores: opt: 286, E(): 9.9e-10, (26.6% identity in 351 aa overlap); P76052|ABGB_ECOLI Aminobenzoyl-glutamate utilizatio from Escherichia coli (481 aa), FASTA scores: opt: 383, E(): 2.1e-15, (30.5% identity in 328 aa overlap); P44765|YDAJ_HAEIN HYPOTHETICAL PROTEIN HI0584 from Haemophilus influenzae (423 aa), FASTA scores: opt: 297, E(): 2.4e-10, (29.6% identity in 274 aa overlap). Note that previously known as amiB. Protein product from Mb3334c detected using SWATH mass spectrometry. Mb3334c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing (TPM > 20)." /db_xref="GOA:A0A1R3Y3S2" /db_xref="InterPro:IPR002933" /db_xref="InterPro:IPR011650" /db_xref="InterPro:IPR017144" /db_xref="InterPro:IPR017439" /db_xref="InterPro:IPR036264" /db_xref="UniProtKB/TrEMBL:A0A1R3Y3S2" BEGIN 1 MPAASASDRV EELVRRRGGE LVELSHAIHA EPELAFAEHR SCAKAQALVA ERGFEITTAA 61 GGLDTAFRAD YGSGPLVVGV CAEYDALPGI GHACGHNIIA ASAVGTALAL AEVADDLGLT 121 VALLGTPAEE SGGGKALMLQ AGTFDDVAVA VMVHPGPTDI AGARSLALSE VTVRYRGKES 181 HAAVAPHLGV NAADAVTVAQ VAIGVLRQQL APGQMVHGIV TDGGQAVNVI PGQARLQYAM 241 RAVESDSLRE LQTRMFACFA AGALAAGCEY EIDEAAPAYA ELKPDPWLAD VCREEMQRLG 301 REPLLPALEA ELPLGSTDMG NVTQVLPGIH PVIGLDAGAA TVHQRAFTVA SAGASADRAV 361 VDGAIMLART VVRLAQTPDE RDRVLAAQQR RAAR //