LOCUS       SIU01939.1               222 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Septum
            formation protein Maf protein.
ACCESSION   LT708304-3353
PROTEIN_ID  SIU01939.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB3310"
                     /note="Mb3310, -, len: 222 aa. Equivalent to Rv3282, len:
                     222 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.5% identity in 222 aa overlap). Conserved hypothetical
                     protein, equivalent to Q49670|ML0729 1308R (HYPOTHETICAL
                     PROTEIN ML0729) from Mycobacterium leprae (213 aa), FASTA
                     scores: opt: 945, E(): 5.5e-54, (68.55% identity in 213 aa
                     overlap). Also similar to Q9EWV6|2SCK31.18 CONSERVED
                     HYPOTHETICAL PROTEIN from Streptomyces coelicolor (206
                     aa), FASTA scores: opt: 459, E(): 1.3e-22, (47.35%
                     identity in 209 aa overlap); P74331|MAF OR SLL0905 MAF
                     PROTEIN from Synechocystis sp. strain PCC 6803 (195 aa),
                     FASTA scores: opt: 401, E(): 6.9e-19, (43.0% identity in
                     207 aa overlap); and shows weak similarity with various
                     proteins e.g. Q9BUL6 ACETYLSEROTONIN
                     O-METHYLTRANSFERASE-LIKE from Homo sapiens (Human) (621
                     aa), FASTA scores: opt: 282, E(): 8.9e-11, (31.6% identity
                     in 193 aa overlap); O95671|ASMTL ASMTL PROTEIN from Homo
                     sapiens (Human) (629 aa), FASTA scores: opt: 282, E():
                     9e-11, (31.6% identity in 193 aa overlap);
                     BAB51136|MLR4491 MAF PROTEIN from Rhizobium loti
                     (Mesorhizobium loti) (199 aa), FASTA scores: opt: 269,
                     E(): 2.3e-10, (29.3% identity in 198 aa overlap); etc.
                     Protein product from Mb3310 detected using SWATH mass
                     spectrometry. Mb3310 found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:Q7TWT7"
                     /db_xref="InterPro:IPR003697"
                     /db_xref="InterPro:IPR029001"
                     /db_xref="UniProtKB/Swiss-Prot:Q7TWT7"
BEGIN
        1 MTRLVLGSAS PGRLKVLRDA GIEPLVIASH VDEDVVIAAL GPDAVPSDVV CVLAAAKAAQ
       61 VATTLTGTQR IVAADCVVVA CDSMLYIEGR LLGKPASIDE AREQWRSMAG RAGQLYTGHG
      121 VIRLQDNKTV YRSAETAITT VYFGTPSASD LEAYLASGES LRVAGGFTLD GLGGWFIDGV
      181 QGNPSNVIGL SLPLLRSLVQ RCGLSVAALW AGNAGGPAHK QQ
//