LOCUS SIU01895.1 244 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN protein. ACCESSION LT708304-3309 PROTEIN_ID SIU01895.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB3266C" /note="Mb3266c, -, len: 244 aa. Equivalent to Rv3238c, len: 244 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 244 aa overlap). Probable conserved integral membrane protein, similar to several hypothetical proteins and transmembrane proteins e.g. Q9UN92|NRM29 MULTISPANNING NUCLEAR ENVELOPE MEMBRANE PROTEIN NURIM (FRAGMENT) from Homo sapiens (Human) (261 aa), FASTA scores: opt: 281, E(): 3.3e-11, (30.7% identity in 189 aa overlap); Q9VEG9|CG7655 HYPOTHETICAL PROTEIN from Drosophila melanogaster (Fruit fly) (253 aa), FASTA scores: opt: 242, E(): 1.1e-08, (27.7% identity in 242 aa overlap); BAB48937|MLR1600 HYPOTHETICAL PROTEIN from Rhizobium loti (Mesorhizobium loti) (222 aa), FASTA scores: opt: 137, E(): 0.066, (28.1% identity in 185 aa overlap); BAB57936|SAV1774 AESENICAL PUMP MEMBRANE PROTEIN HOMOLOG from Staphylococcus aureus subsp. aureus Mu50 (430 aa), FASTA scores: opt: 125, E(): 0.68, (25.7% identity in 144 aa overlap); etc. Protein product from Mb3266c detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb3266c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:A0A1R3Y5B6" /db_xref="InterPro:IPR009915" /db_xref="InterPro:IPR033580" /db_xref="UniProtKB/TrEMBL:A0A1R3Y5B6" BEGIN 1 MKRYLTIIYG AASYLVFLVA FGYAIGFVGD VVVPRTVDHA IAAPIGQAVV VNLVLLGVFA 61 VQHSVMARQG FKRWWTRFVP PSIERSTYVL LASVALLLLY WQWRTMPAVI WDVRQPAGRV 121 ALWALFWLGW ATVLTSTFMI NHFELFGLRQ VYLAWRGKPY TEIGFQAHLL YRWVRHPIML 181 GFVVAFWATP MMTAGHLLFA IGATGYILVA LQFEERDLLA ALGDQYRDYR REVSMLLPWP 241 HRHT //