LOCUS SIU01878.1 183 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 CONSERVED HYPOTHETICAL PROTEIN protein. ACCESSION LT708304-3292 PROTEIN_ID SIU01878.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB3249C" /note="Mb3249c, -, len: 183 aa. Equivalent to Rv3222c, len: 183 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 183 aa overlap). Hypothetical protein, with some similarity to Q9SZD2|F19B15.50|AT4G29020 GLYCINE-RICH PROTEIN LIKE from Arabidopsis thaliana (Mouse-ear cress) (158 aa), FASTA scores: opt: 131, E(): 0.77, (33.35% identity in 126 aa overlap); Q9S222|SCI51.18 PUTATIVE TRANSCRIPTIONAL REGULATOR from Streptomyces coelicolor (548 aa), FASTA scores: opt: 133, E(): 1.6, (36.25% identity in 149 aa overlap); etc. Also some similarity to other hypothetical Mycobacterium tuberculosis proteins e.g. O06292|Rv0341|MTCY13E10.01 (479 aa), FASTA scores: opt: 141, E(): 0.5, (31.2% identity in 170 aa overlap); AAK45760|MT1497.1 PE_PGRS FAMILY PROTEIN from strain CDC1551 (1408 aa), FASTA scores: opt: 137, E(): 2, (31.75% identity in 148 aa overlap); etc. Mb3249c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing (TPM > 20)." /db_xref="UniProtKB/TrEMBL:A0A1R3Y3U1" BEGIN 1 MSSPVSSRRL ANLVKESLQG SVLGGVVSDA VLPAVSDDVK PGAGEDAYRV PVVVAAGSGA 61 VVQVGGLEVG SAAVAGEVAD TVAELFVCRP TEPDVGDFVG LAGGAGDAGQ AGQQFGLGVG 121 VRGESFGARR RLALSTVGAS GATAGLRKTH DGHHGCQARG ALTQRRLYIG NPSEITDTRM 181 VHQ //