LOCUS       SIU01878.1               183 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 CONSERVED
            HYPOTHETICAL PROTEIN protein.
ACCESSION   LT708304-3292
PROTEIN_ID  SIU01878.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB3249C"
                     /note="Mb3249c, -, len: 183 aa. Equivalent to Rv3222c,
                     len: 183 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 183 aa overlap). Hypothetical protein,
                     with some similarity to Q9SZD2|F19B15.50|AT4G29020
                     GLYCINE-RICH PROTEIN LIKE from Arabidopsis thaliana
                     (Mouse-ear cress) (158 aa), FASTA scores: opt: 131, E():
                     0.77, (33.35% identity in 126 aa overlap); Q9S222|SCI51.18
                     PUTATIVE TRANSCRIPTIONAL REGULATOR from Streptomyces
                     coelicolor (548 aa), FASTA scores: opt: 133, E(): 1.6,
                     (36.25% identity in 149 aa overlap); etc. Also some
                     similarity to other hypothetical Mycobacterium
                     tuberculosis proteins e.g. O06292|Rv0341|MTCY13E10.01 (479
                     aa), FASTA scores: opt: 141, E(): 0.5, (31.2% identity in
                     170 aa overlap); AAK45760|MT1497.1 PE_PGRS FAMILY PROTEIN
                     from strain CDC1551 (1408 aa), FASTA scores: opt: 137,
                     E(): 2, (31.75% identity in 148 aa overlap); etc. Mb3249c
                     found to be expressed during exponential growth in
                     Sauton's minimal media by RNA-sequencing (TPM > 20)."
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y3U1"
BEGIN
        1 MSSPVSSRRL ANLVKESLQG SVLGGVVSDA VLPAVSDDVK PGAGEDAYRV PVVVAAGSGA
       61 VVQVGGLEVG SAAVAGEVAD TVAELFVCRP TEPDVGDFVG LAGGAGDAGQ AGQQFGLGVG
      121 VRGESFGARR RLALSTVGAS GATAGLRKTH DGHHGCQARG ALTQRRLYIG NPSEITDTRM
      181 VHQ
//