LOCUS       SIU01876.1                71 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 BIOTINYLATED
            PROTEIN TB7.3 protein.
ACCESSION   LT708304-3290
PROTEIN_ID  SIU01876.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="TB7.3"
                     /locus_tag="BQ2027_MB3247C"
                     /note="Mb3247c, TB7.3, len: 71 aa. Equivalent to Rv3221c,
                     len: 71 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 71 aa overlap). Biotinylated protein
                     TB7.3 (see citation below), equivalent (appears to have
                     one additional residue) to Q9CCH9|ML0802|BTB7_MYCLE
                     BIOTINYLATED PROTEIN TB7.3 HOMOLOG from Mycobacterium
                     leprae (70 aa), FASTA scores: opt: 367, E(): 4e-18, (90.0%
                     identity in 70 aa overlap); Q9XCD6|BTB7_MYCSM BIOTINYLATED
                     PROTEIN TB7.3 HOMOLOG from Mycobacterium smegmatis (70
                     aa), FASTA scores: opt: 341, E(): 2.1e-16, (84.05%
                     identity in 69 aa overlap). Similar to C-terminal part of
                     various proteins e.g. Q9HPP8|ACC|VNG1532G BIOTIN
                     CARBOXYLASE from Halobacterium sp. strain NRC-1 (610 aa),
                     FASTA scores: opt: 212, E(): 4e-07, (50.0% identity in 68
                     aa overlap); Q58628|PYCB_METJA|MJ1231 PYRUVATE CARBOXYLASE
                     SUBUNIT B from Methanococcus jannaschii (567 aa), FASTA
                     scores: opt: 192, E(): 7.8e-06, (44.8% identity in 58 aa
                     overlap); Q9ZAA7|GCDC GLUTACONYL-COA DECARBOXYLASE GAMMA
                     SUBUNIT from Acidaminococcus fermentans (145 aa), FASTA
                     scores: opt: 184, E(): 8.9e-06, (39.4% identity in 66 aa
                     overlap); etc. Mb3247c found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="InterPro:IPR000089"
                     /db_xref="InterPro:IPR011053"
                     /db_xref="UniProtKB/Swiss-Prot:P0A511"
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MAEDVRAEIV ASVLEVVVNE GDQIDKGDVV VLLESMKMEI PVLAEAAGTV SKVAVSVGDV
       61 IQAGDLIAVI S
//