LOCUS       SIU01873.1               321 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Transcription
            regulator [contains diacylglycerol kinase catalytic domain]
            protein.
ACCESSION   LT708304-3287
PROTEIN_ID  SIU01873.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB3244"
                     /note="Mb3244, -, len: 321 aa. Equivalent to Rv3218, len:
                     321 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 321 aa overlap). Conserved
                     hypothetical protein, similar to several hypothetical
                     bacterial proteins e.g. Q9F3M0|2SC7G11.03c from
                     Streptomyces coelicolor (322 aa), FASTA scores: opt: 694,
                     E(): 4.2e-35, (39.95% identity in 328 aa overlap);
                     Q9A0J4|SPY0752 from Streptomyces pyogenes (340 aa), FASTA
                     scores: opt: 187, E(): 0.00033, (30.5% identity in 141 aa
                     overlap); O31502|YERQ from Bacillus subtilis (303 aa),
                     FASTA scores: opt: 184, E(): 0.00045, (34.15% identity in
                     126 aa overlap); etc. Protein product from Mb3244 detected
                     using shotgun mass spectrometry and SWATH mass
                     spectrometry. Mb3244 found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:A0A1R3Y3H1"
                     /db_xref="InterPro:IPR001206"
                     /db_xref="InterPro:IPR016064"
                     /db_xref="InterPro:IPR017438"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y3H1"
BEGIN
        1 MRAVLIVNPT ATATTPAGRD LLAHALESRL QLTVEHTNHR GHGTELGQAA VADGVDLVVV
       61 HGGDGTVSAV VNGMLGRPGT TPVRPVPAVA VVPGGSANVL ARALGISADP IAATNQLIQL
      121 LDDYGRHQQW RRIGLIDCGE RWAVFNAGMG VDAEVVAAVE AERDKGGKVT AWRYIRAAVR
      181 AVLACTRREP ALTLQLPNRD PITGVHFVFV SNSSPWTYAN NRPVWTNPDC RFESGLGVFA
      241 TTSMKVVPTL RVVRQMFAKQ PKFEFNHVIN NDDVACLRVT SMGPPIASQF DGDYLGVRET
      301 MTFRAVPDAL AVVAPPARKR I
//