LOCUS SIU01873.1 321 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 Transcription regulator [contains diacylglycerol kinase catalytic domain] protein. ACCESSION LT708304-3287 PROTEIN_ID SIU01873.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB3244" /note="Mb3244, -, len: 321 aa. Equivalent to Rv3218, len: 321 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 321 aa overlap). Conserved hypothetical protein, similar to several hypothetical bacterial proteins e.g. Q9F3M0|2SC7G11.03c from Streptomyces coelicolor (322 aa), FASTA scores: opt: 694, E(): 4.2e-35, (39.95% identity in 328 aa overlap); Q9A0J4|SPY0752 from Streptomyces pyogenes (340 aa), FASTA scores: opt: 187, E(): 0.00033, (30.5% identity in 141 aa overlap); O31502|YERQ from Bacillus subtilis (303 aa), FASTA scores: opt: 184, E(): 0.00045, (34.15% identity in 126 aa overlap); etc. Protein product from Mb3244 detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb3244 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:A0A1R3Y3H1" /db_xref="InterPro:IPR001206" /db_xref="InterPro:IPR016064" /db_xref="InterPro:IPR017438" /db_xref="UniProtKB/TrEMBL:A0A1R3Y3H1" BEGIN 1 MRAVLIVNPT ATATTPAGRD LLAHALESRL QLTVEHTNHR GHGTELGQAA VADGVDLVVV 61 HGGDGTVSAV VNGMLGRPGT TPVRPVPAVA VVPGGSANVL ARALGISADP IAATNQLIQL 121 LDDYGRHQQW RRIGLIDCGE RWAVFNAGMG VDAEVVAAVE AERDKGGKVT AWRYIRAAVR 181 AVLACTRREP ALTLQLPNRD PITGVHFVFV SNSSPWTYAN NRPVWTNPDC RFESGLGVFA 241 TTSMKVVPTL RVVRQMFAKQ PKFEFNHVIN NDDVACLRVT SMGPPIASQF DGDYLGVRET 301 MTFRAVPDAL AVVAPPARKR I //