LOCUS SIU01835.1 114 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 Toxin HigB protein. ACCESSION LT708304-3249 PROTEIN_ID SIU01835.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="higB3" /locus_tag="BQ2027_MB3208" /note="Mb3208, -, len: 114 aa. Equivalent to Rv3182, len: 114 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 114 aa overlap). Hypothetical protein, with some similarity to other hypothetical bacterial proteins e.g. O53468|Rv2022c|MTV018.09c from M. tuberculosis (201 aa), FASTA scores: opt: 335, E(): 3.6e-16, (51.9% identity in 104 aa overlap); and Q9L3R6|ORF119 from Anabaena sp. strain PCC 7120 (119 aa), FASTA scores: opt: 250, E(): 1.6e-10, (42.1% identity in 95 aa overlap). Equivalent to AAK47614 from Mycobacterium tuberculosis strain CDC1551 (94 aa) but longer 20 aa. Mb3208 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing (TPM > 20)." /db_xref="InterPro:IPR009241" /db_xref="UniProtKB/TrEMBL:A0A1R3Y560" BEGIN 1 MAVILLPQVE RWFFALNRDA MASVTGAIDL LEMEGPTLGR PVVDKVNDST FHNMKELRPA 61 GTSIRILFAF DPARQAILLL GGDKAGNWKR WYDNNIPIAD QRSENWLASE HGGG //