LOCUS       SIU01801.1               445 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            NADH DEHYDROGENASE I (CHAIN F) NUOF (NADH-UBIQUINONE OXIDOREDUCTASE 
            CHAIN F) protein.
ACCESSION   LT708304-3215
PROTEIN_ID  SIU01801.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="nuoF"
                     /locus_tag="BQ2027_MB3174"
                     /note="Mb3174, nuoF, len: 445 aa. Equivalent to Rv3150,
                     len: 445 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 445 aa overlap). Probable nuoF, NADH
                     dehydrogenase, chain F (EC 1.6.5.3), similar to others
                     e.g. Q9XAQ9|NUOF_STRCO from Streptomyces coelicolor (449
                     aa), FASTA scores: opt: 2314, E(): 3.5e-139, (76.25%
                     identity in 434 aa overlap); NUF2_RHIME from Rhizobium
                     meliloti (421 aa), FASTA scores: opt: 1545, E(): 1.8e-90,
                     (53.1% identity in 424 aa overlap); Q9RU92|DR1500 from
                     Deinococcus radiodurans (444 aa), FASTA scores: opt: 1445,
                     E(): 4.1e-84, (52.9% identity in 427 aa overlap); etc.
                     Contains respiratory-chain NADH dehydrogenase 51 Kd
                     subunit signature 2 (PS00645). BELONGS TO THE COMPLEX I 51
                     KDA SUBUNIT FAMILY. COFACTOR: FMN AND ONE 4FE-4S CLUSTER
                     (PROBABLE). Protein product from Mb3174 detected using
                     shotgun mass spectrometry and SWATH mass spectrometry.
                     Mb3174 found to be expressed during exponential growth in
                     Sauton's minimal media by RNA-sequencing."
                     /db_xref="GOA:P65568"
                     /db_xref="InterPro:IPR001949"
                     /db_xref="InterPro:IPR011537"
                     /db_xref="InterPro:IPR011538"
                     /db_xref="InterPro:IPR019554"
                     /db_xref="InterPro:IPR019575"
                     /db_xref="InterPro:IPR037207"
                     /db_xref="InterPro:IPR037225"
                     /db_xref="UniProtKB/Swiss-Prot:P65568"
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MTTQATPLTP VISRHWDDPE SWTLATYQRH DRYRGYQALQ KALTMPPDDV ISIVKDSGLR
       61 GRGGAGFATG TKWSFIPQGD TGAAAKPHYL VVNADESEPG TCKDIPLMLA TPHVLIEGVI
      121 IAAYAIRAHH AFVYVRGEVV PVLRRLHNAV AEAYAAGFLG RNIGGSGFDL ELVVHAGAGA
      181 YICGEETALL DSLEGRRGQP RLRPPFPAVA GLYGCPTVIN NVETIASVPS IILGGIDWFR
      241 SMGSEKSPGF TLYSLSGHVT RPGQYEAPLG ITLRELLDYA GGVRAGHRLK FWTPGGSSTP
      301 LLTDEHLDVP LDYEGVGAAG SMLGTKALEI FDETTCVVRA VRRWTEFYKH ESCGKCTPCR
      361 EGTFWLDKIY ERLETGRGSH EDIDKLLDIS DSILGKSFCA LGDGAASPVM SSIKHFRDEY
      421 LAHVEGGGCP FDPRDSMLVA NGVDA
//