LOCUS       SIU01797.1               184 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            NADH DEHYDROGENASE I (CHAIN B) NUOB (NADH-UBIQUINONE OXIDOREDUCTASE 
            CHAIN B) protein.
ACCESSION   LT708304-3211
PROTEIN_ID  SIU01797.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="nuoB"
                     /locus_tag="BQ2027_MB3170"
                     /note="Mb3170, nuoB, len: 184 aa. Equivalent to Rv3146,
                     len: 184 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 184 aa overlap). Probable nuoB, NADH
                     dehydrogenase, chain B (EC 1.6.5.3), similar to others
                     e.g. Q9XAQ5|NUOB from Streptomyces coelicolor (184 aa),
                     FASTA scores: opt: 989, E(): 1.4e-56, (78.25% identity in
                     184 aa overlap); Q56218|NQO6_THETH|NQO6 from Thermus
                     aquaticus (subsp. thermophilus) (181 aa), FASTA scores:
                     opt: 720, E(): 2.6e-39, (64.45% identity in 152 aa
                     overlap); Q9RU87|DR1505 from Deinococcus radiodurans (181
                     aa), FASTA scores: opt: 719, E(): 3e-39, (62.6% identity
                     in 155 aa overlap); etc. BELONGS TO THE COMPLEX I 20 KDA
                     SUBUNIT FAMILY. MAY CONTAIN AN IRON-SULFUR 4FE-4S CLUSTER.
                     TBparse score is 0.912. Protein product from Mb3170
                     detected using shotgun mass spectrometry and SWATH mass
                     spectrometry. Mb3170 found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:P65576"
                     /db_xref="InterPro:IPR006137"
                     /db_xref="InterPro:IPR006138"
                     /db_xref="UniProtKB/Swiss-Prot:P65576"
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MGLEEQLPGG ILLSTVEKVA GYVRKNSLWP ATFGLACCAI EMMATAGPRF DIARFGMERF
       61 SATPRQADLM IVAGRVSQKM APVLRQIYDQ MAEPKWVLAM GVCASSGGMF NNYAIVQGVD
      121 HVVPVDIYLP GCPPRPEMLL HAILKLHEKI QQMPLGINRE RAIAEAEEAA LLARPTIEMR
      181 GLLR
//