LOCUS       SIU01795.1               409 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 ppe
            family protein ppe52 protein.
ACCESSION   LT708304-3209
PROTEIN_ID  SIU01795.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="PPE52"
                     /locus_tag="BQ2027_MB3168C"
                     /note="Mb3168c, PPE52, len: 409 aa. Equivalent to Rv3144c,
                     len: 409 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.5% identity in 409 aa overlap). Member of the M.
                     tuberculosis PPE family, Gly-, Ala-rich, similar to others
                     e.g. P71868|Rv3533c|MTCY03C7.23 (582 aa), FASTA scores:
                     opt: 1007, E(): 5.2e-35, (56.2% identity in 306 aa
                     overlap); and MTV014_3, MTCY6G11_5, MTCY98.0034c,
                     MTCY31.06c, MTCY48.17, MTCY98.0029c, MTCY03C7.17c, etc.
                     Protein product from Mb3168c detected using SWATH mass
                     spectrometry. Mb3168c found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="InterPro:IPR000030"
                     /db_xref="InterPro:IPR038332"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y535"
BEGIN
        1 MSFVVLPPEI NSLRMFIGAG TAPMLAAAAA WDGLAEELGT AAQSFASVTA GLAGQAWQGP
       61 AALAMAAAAA PYAGWLTAAA AQSAGAAGQA RAVASIFEAA QAATVLPAAV AANRDAFVQL
      121 VMTNLFGQNA PLIAAAEGVY EEMWAADVAA MSGYYSGASA IAAQVVPWAS LLQRFPGLGA
      181 GATGATGGES VGTGATGGES VGTGGGESVG TGGATASGGG VGYVGGGVAS AGLAAGDPAH
      241 GSVGQGNFGG GDVGAGDVVA SSATSAHAGV VSPGFIGAPL ALAALGQMAR GGTNSAPGTA
      301 TESARAPEPA ASAPPEAVVE VPELEVPAMG VLPTVDPKVA AKAAPLSTTR VGQSAGSGIP
      361 ESTLRTAQGQ QASETSAAEE TAPSLRPEAA AGQLRPRVRQ DPKIQMRGG
//