LOCUS SIU01795.1 409 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 ppe family protein ppe52 protein. ACCESSION LT708304-3209 PROTEIN_ID SIU01795.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="PPE52" /locus_tag="BQ2027_MB3168C" /note="Mb3168c, PPE52, len: 409 aa. Equivalent to Rv3144c, len: 409 aa, from Mycobacterium tuberculosis strain H37Rv, (99.5% identity in 409 aa overlap). Member of the M. tuberculosis PPE family, Gly-, Ala-rich, similar to others e.g. P71868|Rv3533c|MTCY03C7.23 (582 aa), FASTA scores: opt: 1007, E(): 5.2e-35, (56.2% identity in 306 aa overlap); and MTV014_3, MTCY6G11_5, MTCY98.0034c, MTCY31.06c, MTCY48.17, MTCY98.0029c, MTCY03C7.17c, etc. Protein product from Mb3168c detected using SWATH mass spectrometry. Mb3168c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="InterPro:IPR000030" /db_xref="InterPro:IPR038332" /db_xref="UniProtKB/TrEMBL:A0A1R3Y535" BEGIN 1 MSFVVLPPEI NSLRMFIGAG TAPMLAAAAA WDGLAEELGT AAQSFASVTA GLAGQAWQGP 61 AALAMAAAAA PYAGWLTAAA AQSAGAAGQA RAVASIFEAA QAATVLPAAV AANRDAFVQL 121 VMTNLFGQNA PLIAAAEGVY EEMWAADVAA MSGYYSGASA IAAQVVPWAS LLQRFPGLGA 181 GATGATGGES VGTGATGGES VGTGGGESVG TGGATASGGG VGYVGGGVAS AGLAAGDPAH 241 GSVGQGNFGG GDVGAGDVVA SSATSAHAGV VSPGFIGAPL ALAALGQMAR GGTNSAPGTA 301 TESARAPEPA ASAPPEAVVE VPELEVPAMG VLPTVDPKVA AKAAPLSTTR VGQSAGSGIP 361 ESTLRTAQGQ QASETSAAEE TAPSLRPEAA AGQLRPRVRQ DPKIQMRGG //