LOCUS       SIU01794.1               133 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            RESPONSE REGULATOR protein.
ACCESSION   LT708304-3208
PROTEIN_ID  SIU01794.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB3167"
                     /note="Mb3167, -, len: 133 aa. Equivalent to Rv3143, len:
                     133 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 133 aa overlap). Probable response
                     regulator, similar to other sensory transduction
                     regulatory proteins e.g. Q9X810|SC6G10.25 from
                     Streptomyces coelicolor (133 aa), FASTA scores: opt: 474,
                     E(): 2.8e-24, (54.15% identity in 120 aa overlap);
                     Q9KZ82|SCE25.04c from Streptomyces coelicolor (225 aa),
                     FASTA scores: opt: 144, E(): 0.016, (32.3% identity in 127
                     aa overlap); Q9RZT4|DRB0029 from Deinococcus radiodurans
                     (416 aa), FASTA scores: opt: 145, E(): 0.024, (30.65%
                     identity in 124 aa overlap). SIMILAR TO OTHER REGULATORY
                     COMPONENTS OF SENSORY TRANSDUCTION SYSTEMS. Protein
                     product from Mb3167 detected using shotgun mass
                     spectrometry. Mb3167 found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:A0A1R3Y395"
                     /db_xref="InterPro:IPR001789"
                     /db_xref="InterPro:IPR011006"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y395"
BEGIN
        1 MPDSSTALRI LVYSDNVQTR ERVMRALGKR LHPDLPDLTY VEVATGPMVI RQMDRGGIDL
       61 AILDGEATPT GGMGIAKQLK DELASCPPIL VLTGRPDDTW LASWSRAEAA VPHPVDPIVL
      121 GRTVLSLLRA PAH
//