LOCUS SIU01773.1 289 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 transcriptional regulatory protein moar1 protein. ACCESSION LT708304-3187 PROTEIN_ID SIU01773.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="moar1" /locus_tag="BQ2027_MB3147" /note="Mb3147, -, len: 289 aa. Equivalent to Rv3124, len: 289 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 289 aa overlap). Probable transcriptional regulatory protein, similar to many Streptomyces and Mycobacterium tuberculosis regulatory proteins e.g. Q11052|YC67_MYCTU|Rv1267c|MT1305|MTCY50.15 from Mycobacterium tuberculosis strain H37Rv (388 aa), FASTA scores: opt: 963, E(): 2e-56, (55.15% identity in 252 aa overlap); O53145 from Mycobacterium tuberculosis (381 aa); P71484|EMBR from Mycobacterium avium (384 aa), FASTA scores: opt: 859, E(): 1.5e-49, (52.2% identity in 249 aa overlap); Q9XCC3|TYLT from Streptomyces fradiae (404 aa), FASTA scores: opt: 462, E(): 3.1e-23, (35.05% identity in 254 aa overlap); Q9XCC4|TYLS from Streptomyces fradiae (277 aa), FASTA scores: opt: 456, E(): 5.6e-23, (33.45% identity in 269 aa overlap); etc. Start chosen by similarity, alternative possible (see AAK47548 from Mycobacterium tuberculosis strain CDC1551, longer N-terminus (311 aa))." /db_xref="GOA:A0A1R3Y367" /db_xref="InterPro:IPR001867" /db_xref="InterPro:IPR005158" /db_xref="InterPro:IPR011990" /db_xref="InterPro:IPR016032" /db_xref="InterPro:IPR036388" /db_xref="UniProtKB/TrEMBL:A0A1R3Y367" BEGIN 1 MQFNVLGPLE LNLRGTKLPL GTPKQRAVLA MLLLSRNQVV AADALVQAIW EKSPPARARR 61 TVHTYICNLR RTLSDAGVDS RNILVSEPPG YRLLIGDRQQ CDLDRFVAAK ESGLRASAKG 121 YFSEAIRYLD SALQNWRGPV LGDLRSFMFV QMFSRALTED ELLVHTKLAE AAIACGRADV 181 VIPKLERLVA MHPYRESLWK QLMLGYYVNE YQSAAIDAYH RLKSTLAEEL GVEPAPTIRA 241 LYHKILRQLP MDDLVGRVTR GRVDLRGGNG AKVEELTESD KDLLPIGLA //