LOCUS SIU01763.1 131 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE PTERIN-4-ALPHA-CARBINOLAMINE DEHYDRATASE MOAB1 (PHS) ( 4-ALPHA-HYDROXY-TETRAHYDROPTERIN DEHYDRATASE) (PTERIN- 4-A-CARBINOLAMINE DEHYDRATASE) (PHENYLALANINE HYDROXYLASE- STIMULATING PROTEIN) (PHS) (PTERIN CARBINOLAMINE DEHYDRATASE) (PCD) protein. ACCESSION LT708304-3177 PROTEIN_ID SIU01763.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="moaB1" /locus_tag="BQ2027_MB3137" /standard_name="moaB" /note="Mb3137, moaB1, len: 131 aa. Equivalent to Rv3110, len: 131 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 131 aa overlap). Probable moaB1, pterin-4-alpha-carbinolamine dehydratase (EC 4.2.1.96), similar to others e.g. P73790|SSL2296 from Synechocystis sp. strain PCC 6803 (96 aa), FASTA scores: opt: 195, E(): 6.2e-07, (35.4% identity in 96 aa overlap); Q9PAB4|PHS_XYLFA|XF2604 from Xylella fastidiosa (116 aa), FASTA scores: opt: 187, E(): 2.6e-06, (36.25% identity in 102 aa overlap); AAK42360|Q97WM6|PHS_SULSO|SSO2187 from Sulfolobus solfataricus (114 aa), FASTA scores: opt: 177, E(): 1.3e-05, (34.6% identity in 78 aa overlap); etc. Also highly similar to AAK47768|MT3426 PTERIN-4-ALPHA-CARBINOLAMINE DEHYDRATASE from Mycobacterium tuberculosis CDC1551 (124 aa), FASTA scores: opt: 383, E(): 7.7e-20, (50.0% identity in 110 aa overlap). BELONGS TO THE PTERIN-4-ALPHA-CARBINOLAMINE DEHYDRATASE FAMILY. Note that previously known as moaB." /db_xref="GOA:A0A1R3Y357" /db_xref="InterPro:IPR001533" /db_xref="InterPro:IPR036428" /db_xref="UniProtKB/TrEMBL:A0A1R3Y357" BEGIN 1 MTVSTPEQHE QRASHDASEG KHNVCQGRLA ALADAAVSEK LGALPGWQLL DMRLSRAFQC 61 TNFDQSIDFM NRVASIANDI NHHPDIAVLD KRSVRVTAWT RKLGYLTDID FDLAASVEAM 121 YATEFADRPA R //