LOCUS       SIU01763.1               131 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            PTERIN-4-ALPHA-CARBINOLAMINE DEHYDRATASE MOAB1 (PHS) (
            4-ALPHA-HYDROXY-TETRAHYDROPTERIN DEHYDRATASE) (PTERIN-
            4-A-CARBINOLAMINE DEHYDRATASE) (PHENYLALANINE HYDROXYLASE-
            STIMULATING PROTEIN) (PHS) (PTERIN CARBINOLAMINE DEHYDRATASE)
            (PCD) protein.
ACCESSION   LT708304-3177
PROTEIN_ID  SIU01763.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="moaB1"
                     /locus_tag="BQ2027_MB3137"
                     /standard_name="moaB"
                     /note="Mb3137, moaB1, len: 131 aa. Equivalent to Rv3110,
                     len: 131 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 131 aa overlap). Probable moaB1,
                     pterin-4-alpha-carbinolamine dehydratase (EC 4.2.1.96),
                     similar to others e.g. P73790|SSL2296 from Synechocystis
                     sp. strain PCC 6803 (96 aa), FASTA scores: opt: 195, E():
                     6.2e-07, (35.4% identity in 96 aa overlap);
                     Q9PAB4|PHS_XYLFA|XF2604 from Xylella fastidiosa (116 aa),
                     FASTA scores: opt: 187, E(): 2.6e-06, (36.25% identity in
                     102 aa overlap); AAK42360|Q97WM6|PHS_SULSO|SSO2187 from
                     Sulfolobus solfataricus (114 aa), FASTA scores: opt: 177,
                     E(): 1.3e-05, (34.6% identity in 78 aa overlap); etc. Also
                     highly similar to AAK47768|MT3426
                     PTERIN-4-ALPHA-CARBINOLAMINE DEHYDRATASE from
                     Mycobacterium tuberculosis CDC1551 (124 aa), FASTA scores:
                     opt: 383, E(): 7.7e-20, (50.0% identity in 110 aa
                     overlap). BELONGS TO THE PTERIN-4-ALPHA-CARBINOLAMINE
                     DEHYDRATASE FAMILY. Note that previously known as moaB."
                     /db_xref="GOA:A0A1R3Y357"
                     /db_xref="InterPro:IPR001533"
                     /db_xref="InterPro:IPR036428"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y357"
BEGIN
        1 MTVSTPEQHE QRASHDASEG KHNVCQGRLA ALADAAVSEK LGALPGWQLL DMRLSRAFQC
       61 TNFDQSIDFM NRVASIANDI NHHPDIAVLD KRSVRVTAWT RKLGYLTDID FDLAASVEAM
      121 YATEFADRPA R
//