LOCUS SIU01755.1 229 aa PRT BCT 25-MAY-2020
DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PUTATIVE
CELL DIVISION ATP-BINDING PROTEIN FTSE (SEPTATION COMPONENT-
TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER) protein.
ACCESSION LT708304-3169
PROTEIN_ID SIU01755.1
SOURCE Mycobacterium tuberculosis variant bovis AF2122/97
ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE 1
AUTHORS Malone K.M.
JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary
Medicine, Tuberculosis Molecular Microbiology Research Group,
University College Dublin, Tuberculosis Molecular Microbiology
Research Group, School of Veterinary Medicine, University College
Dublin, D4, Ireland
REFERENCE 2
AUTHORS Malone M K., Farrell D., Malone K.
JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary
Medicine, Tuberculosis Molecular Microbiology Research Group,
University College Dublin, Tuberculosis Molecular Microbiology
Research Group, School of Veterinary Medicine,, University College
Dublin, D4, Ireland
FEATURES Qualifiers
source /organism="Mycobacterium tuberculosis variant bovis
AF2122/97"
/chromosome="Mycobacterium_bovis_AF212297"
/isolate="AF2122/97"
/mol_type="genomic DNA"
/isolation_source="Mycobacterium bovis subsp. bovis strain
AF2122/97. This strain is a fully virulent strain that was
isolated in 1997 in the UK from a cow suffering necrotic
lesions in lung and bronchomediastinal lymph nodes. The
strain was also reported to infect and persist in badgers
that are considered to be a significant source of bovine
infection."
/db_xref="taxon:233413"
protein /transl_table=11
/gene="ftsE"
/locus_tag="BQ2027_MB3129C"
/note="Mb3129c, ftsE, len: 229 aa. Equivalent to Rv3102c,
len: 229 aa, from Mycobacterium tuberculosis strain H37Rv,
(100.0% identity in 229 aa overlap). Putative ftsE, cell
division protein, septation component transport
ATP-binding protein ABC transporter (see citations below),
equivalent to O32883|FTSE|ML0669 CELL DIVISION ATP-BINDING
PROTEIN from Mycobacterium leprae (229 aa), FASTA scores:
opt: 1384, E(): 2.4e-74, (91.7% identity in 229 aa
overlap); and similar to Q9L1S6|FTSE from Streptomyces
coelicolor (229 aa), FASTA scores: opt: 914, E(): 8.7e-47,
(62.85% identity in 226 aa overlap); Q9A0S4|FTSE|SPY0644
from Streptococcus pyogenes (230 aa), FASTA scores: opt:
866, E(): 5.7e-44, (57.9% identity in 228 aa overlap);
Q9CGX0|FTSE from Lactococcus lactis (subsp. lactis)
(Streptococcus lactis) (230 aa), FASTA scores: opt: 792,
E(): 1.3e-39, (52.2% identity in 228 aa overlap); etc.
Other relatives from Mycobacterium tuberculosis include:
MTCY253.24; MTCY16B7.10; MTCY9C4.04c; MTCY50.01;
MTCY05A6.09c; MTCY04C12.31. Contains PS00017
ATP/GTP-binding site motif A (P-loop) and ABC transporters
family signature (PS00211). BELONG TO THE ATP-BINDING
TRANSPORT PROTEIN FAMILY (ABC TRANSPORTERS). Protein
product from Mb3129c detected using shotgun mass
spectrometry. Mb3129c found to be expressed during
exponential growth in Sauton's minimal media by
RNA-sequencing."
/db_xref="GOA:A0A1R3Y512"
/db_xref="InterPro:IPR003439"
/db_xref="InterPro:IPR003593"
/db_xref="InterPro:IPR005286"
/db_xref="InterPro:IPR017871"
/db_xref="InterPro:IPR027417"
/db_xref="UniProtKB/TrEMBL:A0A1R3Y512"
/experiment="experimental evidence, no additional details
recorded"
BEGIN
1 MITLDHVTKQ YKSSARPALD DINVKIDKGE FVFLIGPSGS GKSTFMRLLL AAETPTSGDV
61 RVSKFHVNKL RGRHVPKLRQ VIGCVFQDFR LLQQKTVYDN VAFALEVIGK RTDAINRVVP
121 EVLETVGLSG KANRLPDELS GGEQQRVAIA RAFVNRPLVL LADEPTGNLD PETSRDIMDL
181 LERINRTGTT VLMATHDHHI VDSMRQRVVE LSLGRLVRDE QRGVYGMDR
//