LOCUS SIU01749.1 437 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 pe- pgrs family protein, triacylglycerol lipase lipy (esterase/ lipase) (triglyceride lipase) (tributyrase) protein. ACCESSION LT708304-3163 PROTEIN_ID SIU01749.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="lipy" /locus_tag="BQ2027_MB3124C" /note="Mb3124c, PE_PGRS63, len: 437 aa. Equivalent to Rv3097c, len: 437 aa, from Mycobacterium tuberculosis strain H37Rv, (99.8% identity in 437 aa overlap). Probable Triacylglycerol lipase (EC 3.1.1.3), and member of the M. tuberculosis PE-family PGRS subfamily of gly-rich proteins; N-terminal part similar to N-terminus of M. tuberculosis PE-PGRS family members e.g. Q10637|Y03A_MYCTU hypothetical glycine-rich 49.6 kd protein (603 aa). Other relatives include MTCY1A11.25c; MTCY21B4.13c; MTCY270.06; MTCY359.33; MTC1A11.04. Mb3124c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:A0A1R3Y333" /db_xref="InterPro:IPR000084" /db_xref="InterPro:IPR013094" /db_xref="InterPro:IPR029058" /db_xref="UniProtKB/TrEMBL:A0A1R3Y333" BEGIN 1 MVSYVVALPE VMSAAATDVA SIGSVVATAS QGVAGATTTV LAAAEDEVSA AIAALFSAHG 61 QDYQALSAQL AVFHERFVQA LTGAAKGYAA AELANASLLQ SEFASGIGNG FATIHQEIQR 121 APTALAAGFT QVPPFAAAQA GIFTGTPSGA AGFDIASLWP VKPLLSLSAL ETHFAIPNNP 181 LLALIASDIP PLSWFLGNSP PPLLNSLLGQ TVQYTTYDGM SVVQITPAHP TGEYVVAIHG 241 GAFILPPSIF HWLNYSVTAY QTGATVQVPI YPLVQEGGTA GTVVPAMAGL ISTQIAQHGV 301 SNVSVVGDSA GGNLALAAAQ YMVSQGNPVP SSMVLLSPWL DVGTWQISQA WAGNLAVNDP 361 LVSPLYGSLN GLPPTYVYSG SLDPLAQQAV VLEHTAVVQG APFSFVLAPW QIHDWILLTP 421 WGLLSWPQIN QQLGIAA //