LOCUS       SIU01749.1               437 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 pe-
            pgrs family protein, triacylglycerol lipase lipy (esterase/
            lipase) (triglyceride lipase) (tributyrase) protein.
ACCESSION   LT708304-3163
PROTEIN_ID  SIU01749.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="lipy"
                     /locus_tag="BQ2027_MB3124C"
                     /note="Mb3124c, PE_PGRS63, len: 437 aa. Equivalent to
                     Rv3097c, len: 437 aa, from Mycobacterium tuberculosis
                     strain H37Rv, (99.8% identity in 437 aa overlap). Probable
                     Triacylglycerol lipase (EC 3.1.1.3), and member of the M.
                     tuberculosis PE-family PGRS subfamily of gly-rich
                     proteins; N-terminal part similar to N-terminus of M.
                     tuberculosis PE-PGRS family members e.g. Q10637|Y03A_MYCTU
                     hypothetical glycine-rich 49.6 kd protein (603 aa). Other
                     relatives include MTCY1A11.25c; MTCY21B4.13c; MTCY270.06;
                     MTCY359.33; MTC1A11.04. Mb3124c found to be expressed
                     during exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:A0A1R3Y333"
                     /db_xref="InterPro:IPR000084"
                     /db_xref="InterPro:IPR013094"
                     /db_xref="InterPro:IPR029058"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y333"
BEGIN
        1 MVSYVVALPE VMSAAATDVA SIGSVVATAS QGVAGATTTV LAAAEDEVSA AIAALFSAHG
       61 QDYQALSAQL AVFHERFVQA LTGAAKGYAA AELANASLLQ SEFASGIGNG FATIHQEIQR
      121 APTALAAGFT QVPPFAAAQA GIFTGTPSGA AGFDIASLWP VKPLLSLSAL ETHFAIPNNP
      181 LLALIASDIP PLSWFLGNSP PPLLNSLLGQ TVQYTTYDGM SVVQITPAHP TGEYVVAIHG
      241 GAFILPPSIF HWLNYSVTAY QTGATVQVPI YPLVQEGGTA GTVVPAMAGL ISTQIAQHGV
      301 SNVSVVGDSA GGNLALAAAQ YMVSQGNPVP SSMVLLSPWL DVGTWQISQA WAGNLAVNDP
      361 LVSPLYGSLN GLPPTYVYSG SLDPLAQQAV VLEHTAVVQG APFSFVLAPW QIHDWILLTP
      421 WGLLSWPQIN QQLGIAA
//