LOCUS SIU01748.1 379 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 putative cellulase family protein. ACCESSION LT708304-3162 PROTEIN_ID SIU01748.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB3123" /note="Mb3123, -, len: 379 aa. Equivalent to Rv3096, len: 379 aa, from Mycobacterium tuberculosis strain H37Rv, (99.7% identity in 379 aa overlap). Hypothetical protein, with slight similarity to several proteins e.g. Q09671|OYEB_SCHPO|SPAC5H10.10 PUTATIVE NADPH DEHYDROGENASE C5H10.10 (EC 1.6.99.1) (OLD YELLOW ENZYME HOMOLOG) from Schizosaccharomyces pombe (Fission yeast) (392 aa), FASTA scores: opt: 125, E(): 1.1, (25.45% identity in 165 aa overlap); and Q12603|XYNA_DICTH BETA-1,4-XYLANASE (EC 3.2.1.8) (ENDO-1,4-BETA-XYLANASE) from Dictyoglomus thermophilum (352 aa), FASTA scores: opt: 124, E(): 1.2, (25.65% identity in 195 aa overlap); etc. Contains glycosyl hydrolases family 5 signature (PS00659). TBparse score is 0.932. Protein product from Mb3123 detected using SWATH mass spectrometry. Mb3123 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="InterPro:IPR017853" /db_xref="UniProtKB/TrEMBL:A0A1R3Y3G2" /experiment="experimental evidence, no additional details recorded" BEGIN 1 MHRRTALKLP LLLAAGTVLG QAPRAAAGEP GRWSADRAHR WYQAHGWLVG ANYITSNAIN 61 QLEMFQPGTY DPRRIDNELG LARFHGFNTV RVFLHDLLWA QDAPGFQTRL AQFVAIAARY 121 HIKPLFVLFD SCWDPLPRPG RQRAPRAGVH NSGWVQSPGA ERLDDRRYAS TLYNYVTGVL 181 GQFRNDDRVL GWDLWNEPDN PARVYRKVER KDKLERVAEL LPQVFRWART VDPVQPLTSG 241 VWQGNWGDPG RRSTISAIQL DNADVITFHS YAAPAEFEGR IAELAPLQRP ILCTEYLARS 301 QGSTVEGILP IAKRHNVGAF NWGLVAGKTQ TYLPWDSWDH PYRAPPKVWF HDLLHPNGRP 361 YRDGEVQTIR KLNGMPSQD //