LOCUS       SIU01748.1               379 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 putative
            cellulase family protein.
ACCESSION   LT708304-3162
PROTEIN_ID  SIU01748.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB3123"
                     /note="Mb3123, -, len: 379 aa. Equivalent to Rv3096, len:
                     379 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.7% identity in 379 aa overlap). Hypothetical protein,
                     with slight similarity to several proteins e.g.
                     Q09671|OYEB_SCHPO|SPAC5H10.10 PUTATIVE NADPH DEHYDROGENASE
                     C5H10.10 (EC 1.6.99.1) (OLD YELLOW ENZYME HOMOLOG) from
                     Schizosaccharomyces pombe (Fission yeast) (392 aa), FASTA
                     scores: opt: 125, E(): 1.1, (25.45% identity in 165 aa
                     overlap); and Q12603|XYNA_DICTH BETA-1,4-XYLANASE (EC
                     3.2.1.8) (ENDO-1,4-BETA-XYLANASE) from Dictyoglomus
                     thermophilum (352 aa), FASTA scores: opt: 124, E(): 1.2,
                     (25.65% identity in 195 aa overlap); etc. Contains
                     glycosyl hydrolases family 5 signature (PS00659). TBparse
                     score is 0.932. Protein product from Mb3123 detected using
                     SWATH mass spectrometry. Mb3123 found to be expressed
                     during exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="InterPro:IPR017853"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y3G2"
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MHRRTALKLP LLLAAGTVLG QAPRAAAGEP GRWSADRAHR WYQAHGWLVG ANYITSNAIN
       61 QLEMFQPGTY DPRRIDNELG LARFHGFNTV RVFLHDLLWA QDAPGFQTRL AQFVAIAARY
      121 HIKPLFVLFD SCWDPLPRPG RQRAPRAGVH NSGWVQSPGA ERLDDRRYAS TLYNYVTGVL
      181 GQFRNDDRVL GWDLWNEPDN PARVYRKVER KDKLERVAEL LPQVFRWART VDPVQPLTSG
      241 VWQGNWGDPG RRSTISAIQL DNADVITFHS YAAPAEFEGR IAELAPLQRP ILCTEYLARS
      301 QGSTVEGILP IAKRHNVGAF NWGLVAGKTQ TYLPWDSWDH PYRAPPKVWF HDLLHPNGRP
      361 YRDGEVQTIR KLNGMPSQD
//