LOCUS SIU01730.1 133 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE HYDROXYLAMINOBENZENE MUTASE HAB protein. ACCESSION LT708304-3144 PROTEIN_ID SIU01730.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="hab" /locus_tag="BQ2027_MB3105" /note="Mb3105, hab, len: 133 aa. Equivalent to Rv3078, len: 133 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 133 aa overlap). Probable hab, hydroxylaminobenzene mutase (5.-.-.-) (see experiments in first citation), highly similar to two hydroxylaminobenzene mutases from Pseudomonas pseudoalcaligenes O52214|HABA (135 aa), FASTA scores: opt: 495, E(): 6.8e-25, (51.1% identity in 133 aa overlap); and O52216|HABB (164 aa), FASTA scores: opt: 479, E(): 8.2e-24, (51.9% identity in 133 aa overlap) (see first citation); and to Q9AH35|NBZB HYDROXYLAMINOBENZENE MUTASE from Pseudomonas putida (164 aa), FASTA scores: opt: 476, E(): 1.3e-23, (51.8% identity in 133 aa overlap) (see second citation). Gene name according to Pseudomonas pseudoalcaligenes nomenclature. Also similarity with putative different membrane proteins involved in transport (protein predicted to be a transmembrane protein). Mb3105 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing (TPM > 20)." /db_xref="GOA:A0A1R3Y334" /db_xref="UniProtKB/TrEMBL:A0A1R3Y334" BEGIN 1 MQKLLFTIGL ALFLIGLLTG LVIPALKNPR MALSSHLEGV LNGMFLVVLG LLWPHIDLPE 61 AWQVIAVALI VYSAYANWLA TLLAAAWGAG RKFAPIATGD HKAPAAKEGF VSFLLLSLSV 121 AIVIGVVIVI IGL //