LOCUS       SIU01721.1               132 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            CONSERVED TRANSMEMBRANE PROTEIN protein.
ACCESSION   LT708304-3135
PROTEIN_ID  SIU01721.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB3096"
                     /note="Mb3096, -, len: 132 aa. Equivalent to Rv3069, len:
                     132 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 132 aa overlap). Probable conserved
                     transmembrane protein, similar to several hypothetical and
                     CRCB bacterial proteins e.g. Q9A6V2|CC1981 CRCB PROTEIN
                     (see citation below; seems to be involved in camphor
                     resistance and chromosome condensation, promoting or
                     protecting chromosome folding) from Caulobacter crescentus
                     (127 aa), FASTA scores: opt: 275, E(): 1.6e-11, (41.1%
                     identity in 124 aa overlap); Q9FC39|SC4G1.10 PUTATIVE
                     INTEGRAL MEMBRANE PROTEIN from Streptomyces coelicolor
                     (154 aa), FASTA scores: opt: 258, E(): 2.5e-10, (42.15%
                     identity in 121 aa overlap); Q9V0X2|PAB1925 CRCB PROTEIN
                     (see citation below) from Pyrococcus abyssi (123 aa),
                     FASTA scores: opt: 256, E(): 2.8e-10, (39.8% identity in
                     113 aa overlap); O59171|PH1502 HYPOTHETICAL 13.6 KDA
                     PROTEIN from Pyrococcus horikoshii (123 aa), FASTA scores:
                     opt: 249, E(): 8.2e-10, (38.65% identity in 119 aa
                     overlap); etc. Mb3096 found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:P63863"
                     /db_xref="InterPro:IPR003691"
                     /db_xref="UniProtKB/Swiss-Prot:P63863"
BEGIN
        1 MPNHDYRELA AVFAGGALGA LARAALSALA IPDPARWPWP TFTVNVVGAF LVGYFTTRLL
       61 ERLPLSSYRR PLLGTGLCGG LTTFSTMQVE TISMIEHGHW GLAAAYSVVS ITLGLLAVHL
      121 ATVLVRRVRI RR
//