LOCUS       SIU01704.1                79 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            GLUTAREDOXIN ELECTRON TRANSPORT COMPONENT OF NRDEF (GLUTAREDOXIN-
            LIKE PROTEIN) NRDH protein.
ACCESSION   LT708304-3118
PROTEIN_ID  SIU01704.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="nrdH"
                     /locus_tag="BQ2027_MB3079C"
                     /note="Mb3079c, nrdH, len: 79 aa. Equivalent to Rv3053c,
                     len: 79 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 79 aa overlap). Probable nrdH,
                     glutaredoxin-like protein, equivalent to
                     Q9CBP8|NRDH|ML1736 from Mycobacterium leprae (80 aa),
                     FASTA scores: opt: 478, E(): 2.7e-27, (91.15% identity in
                     79 aa overlap), and similar to many glutaredoxin-like
                     proteins e.g. Q9XD65|NRDH from Corynebacterium glutamicum
                     (Brevibacterium flavum) (77 aa), FASTA scores: opt: 382,
                     E(): 1.5e-20, (72.35% identity in 76 aa overlap); and
                     Q56108|NRDH_SALTY from Salmonella typhimurium (81 aa),
                     FASTA scores: opt: 243, E(): 9.9e-11, (45.85% identity in
                     72 aa overlap). BELONGS TO THE GLUTAREDOXIN FAMILY.
                     Protein product from Mb3079c detected using SWATH mass
                     spectrometry. Mb3079c found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:A0A1R3Y306"
                     /db_xref="InterPro:IPR002109"
                     /db_xref="InterPro:IPR011909"
                     /db_xref="InterPro:IPR036249"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y306"
BEGIN
        1 MTVTVYTKPA CVQCSATSKA LDKQGIAYQK VDISLDSEAR DYVMALGYLQ APVVVAGNDH
       61 WSGFRPDRIK ALAGAALTA
//