LOCUS       SIU01701.1               246 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY ASNC-FAMILY)
            protein.
ACCESSION   LT708304-3115
PROTEIN_ID  SIU01701.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB3076C"
                     /note="Mb3076c, -, len: 246 aa. Equivalent to Rv3050c,
                     len: 246 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 246 aa overlap). Probable
                     transcriptional regulatory protein tetR-family, equivalent
                     but shorter to Q9CBQ1|ML1733 from Mycobacterium leprae
                     (275 aa), FASTA scores: opt: 1381,(E): 2.7e-79, (86.25%
                     identity in 240 aa overlap); AAK44712|MT0489 from
                     Mycobacterium tuberculosis strain CDC1551 (256 aa), FASTA
                     scores: opt: 328,(E): 1.8e-13, (30.75% identity in 234 aa
                     overlap); etc. Also some similarity to
                     O53757|Rv0472c|MTV038.16c. Alternative starts possible at
                     68052 or 67923. Has potential helix-turn-helix motif at
                     positons 51-72. Protein product from Mb3076c detected
                     using shotgun mass spectrometry and SWATH mass
                     spectrometry. Mb3076c found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:A0A1R3Y2Z4"
                     /db_xref="InterPro:IPR001647"
                     /db_xref="InterPro:IPR009057"
                     /db_xref="InterPro:IPR036271"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y2Z4"
BEGIN
        1 MVRIPRPHPS AKPGVKVDAR SERWREHRKK VRNEIVDAAF RAIDRLGPEL SVRQIAEEAG
       61 TAKPKIYRHF TDKSDLLEAI GMRLRDMLWA AIFPSLDLAT DSAREVIRRS VEEYVNLVDQ
      121 HPNVLRVFIQ GRSAKQSEAT VRTLNEGREI TLAMAEMFNN ELREMELNRA ALELAAFAAF
      181 GSAASATEWW LGPEPDSPRR MPREQFVAHL TTIMMGVIVG TAEALGIAVD PDQPIHDAVP
      241 NNPAVR
//