LOCUS       SIU01689.1               327 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Methyltransferase
            Rv3038c, type 11 protein.
ACCESSION   LT708304-3103
PROTEIN_ID  SIU01689.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB3064C"
                     /note="Mb3064c, -, len: 327 aa. Equivalent to Rv3038c,
                     len: 327 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 327 aa overlap). Conserved
                     hypothetical protein, equivalent to Q9CBQ9|ML1723
                     HYPOTHETICAL PROTEIN from Mycobacterium leprae (327 aa),
                     FASTA scores: opt: 1843, E(): 6.1e-108, (80.75% identity
                     in 327 aa overlap). Weak similarity with e.g.
                     Q9KZI3|SCG8A.16 PUTATIVE METHYLTRANSFERASE from
                     Streptomyces coelicolor (199 aa), FASTA scores: opt: 227,
                     E(): 3.9e-07, (31.95% identity in 191 aa overlap) and
                     O52570 METHYLTRANSFERASE from Amycolatopsis mediterranei
                     (272 aa), FASTA scores: opt: 228, E(): 4.3e-07, (31.7%
                     identity in 164 aa overlap). Contains PS00044 Bacterial
                     regulatory proteins, lysR family signature but shows no
                     similarity to known LysR family members. Protein product
                     from Mb3064c detected using shotgun mass spectrometry and
                     SWATH mass spectrometry. Mb3064c found to be expressed
                     during exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:A0A1R3Y2X3"
                     /db_xref="InterPro:IPR013216"
                     /db_xref="InterPro:IPR029063"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y2X3"
BEGIN
        1 MTRSSNIPAD ATPNPHATAE QVAAARHDSK LAQVLYHDWE AENYDEKWSI SYDQRCVDYA
       61 RGRFDAIVPD EVIAQLPYDR ALELGCGTGF FLLNLIQAGV ARRGSVTDLS PGMVKVATRN
      121 GQALGLDIDG RVADAEGIPY DDDAFDLVVG HAVLHHIPDV ELSLREVVRV LKPGGRFVFA
      181 GEPTTVGDGY ARTLSTLTWR VVTNATKLPG LRGWRRPQGE LDESSRAAAL EALVDLHTFT
      241 PQDLQRIAHN AGAVEVQTAT EEFTAAMLGW PLRTFECTVP PGRLGWGWAR FAFTSWKTLG
      301 WVDANVWRHV VPKGWFYNVM ITGVKPS
//