LOCUS SIU01658.1 509 aa PRT BCT 25-MAY-2020
DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE (SUBUNIT B) GATB (
Glu-ADT SUBUNIT B) protein.
ACCESSION LT708304-3072
PROTEIN_ID SIU01658.1
SOURCE Mycobacterium tuberculosis variant bovis AF2122/97
ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE 1
AUTHORS Malone K.M.
JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary
Medicine, Tuberculosis Molecular Microbiology Research Group,
University College Dublin, Tuberculosis Molecular Microbiology
Research Group, School of Veterinary Medicine, University College
Dublin, D4, Ireland
REFERENCE 2
AUTHORS Malone M K., Farrell D., Malone K.
JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary
Medicine, Tuberculosis Molecular Microbiology Research Group,
University College Dublin, Tuberculosis Molecular Microbiology
Research Group, School of Veterinary Medicine,, University College
Dublin, D4, Ireland
FEATURES Qualifiers
source /organism="Mycobacterium tuberculosis variant bovis
AF2122/97"
/chromosome="Mycobacterium_bovis_AF212297"
/isolate="AF2122/97"
/mol_type="genomic DNA"
/isolation_source="Mycobacterium bovis subsp. bovis strain
AF2122/97. This strain is a fully virulent strain that was
isolated in 1997 in the UK from a cow suffering necrotic
lesions in lung and bronchomediastinal lymph nodes. The
strain was also reported to infect and persist in badgers
that are considered to be a significant source of bovine
infection."
/db_xref="taxon:233413"
protein /transl_table=11
/gene="gatB"
/locus_tag="BQ2027_MB3034C"
/note="Mb3034c, gatB, len: 509 aa. Equivalent to Rv3009c,
len: 509 aa, from Mycobacterium tuberculosis strain H37Rv,
(100.0% identity in 509 aa overlap). Probable gatB,
Glu-tRNA-Gln amidotransferase, subunit B (EC 6.3.5.-),
equivalent to O33107|GATB_MYCLE|MLCB637_15
GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE from Mycobacterium
leprae (509 aa), FASTA scores: opt: 2973, E(): 2.9e-173,
(88.4% identity in 509 aa overlap). Also highly similar to
other Glu- tRNA-Gln amidotransferases e.g.
Q9Z578|GATB|SC8D9.13 from Streptomyces coelicolor (504
aa), FASTA scores: opt: 2264, E(): 3.6e-130, (66.0%
identity in 495 aa overlap); P74215|GATB_SYNY3|SLL1435
from Synechocystis sp. strain PCC 6803 (519 aa), FASTA
scores: opt: 1289, E(): 6.7e-71, (42.0% identity in 485 aa
overlap); Q9X100|GATB_THEMA|TM1273 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE from Thermotoga maritima (482 aa), FASTA
scores: opt: 1165, E(): 2.2e-63, (40.05% identity in 487
aa overlap); etc. For more information about function, see
citation below. Similar to many members of the pet112
family. BELONGS TO THE GATB FAMILY. Protein product from
Mb3034c detected using shotgun mass spectrometry and SWATH
mass spectrometry. Mb3034c found to be expressed during
exponential growth in Sauton's minimal media by
RNA-sequencing."
/db_xref="GOA:P64200"
/db_xref="InterPro:IPR003789"
/db_xref="InterPro:IPR004413"
/db_xref="InterPro:IPR006075"
/db_xref="InterPro:IPR014746"
/db_xref="InterPro:IPR017958"
/db_xref="InterPro:IPR017959"
/db_xref="InterPro:IPR018027"
/db_xref="InterPro:IPR023168"
/db_xref="InterPro:IPR042114"
/db_xref="UniProtKB/Swiss-Prot:P64200"
BEGIN
1 MTVAAGAAKA AGAELLDYDE VVARFQPVLG LEVHVELSTA TKMFCGCTTT FGGEPNTQVC
61 PVCLGLPGSL PVLNRAAVES AIRIGLALNC EIVPWCRFAR KNYFYPDMPK NYQISQYDEP
121 IAINGYLDAP LEDGTTWRVE IERAHMEEDT GKLTHIGSET GRIHGATGSL IDYNRAGVPL
181 IEIVTKPIVG AGARAPQIAR SYVTALRDLL RALDVSDVRM DQGSMRCDAN VSLKPAGTTE
241 FGTRTETKNV NSLKSVEVAV RYEMQRQGAI LASGGRITQE TRHFHEAGYT SAGRTKETAE
301 DYRYFPEPDL EPVAPSRELV ERLRQTIPEL PWLSRRRIQQ EWGVSDEVMR DLVNAGAVEL
361 VAATVEHGAS SEAARAWWGN FLAQKANEAG IGLDELAITP AQVAAVVALV DEGKLSNSLA
421 RQVVEGVLAG EGEPEQVMTA RGLALVRDDS LTQAAVDEAL AANPDVADKI RGGKVAAAGA
481 IVGAVMKATR GQADAARVRE LVLEACGQG
//