LOCUS       SIU01654.1               279 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Membrane
            protein 2, distant similarity to thiosulphate:quinone
            oxidoreductase DoxD protein.
ACCESSION   LT708304-3068
PROTEIN_ID  SIU01654.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB3030C"
                     /note="Mb3030c, -, len: 279 aa. Equivalent to Rv3005c,
                     len: 279 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 279 aa overlap). Conserved
                     hypothetical protein, equivalent to
                     O33110|MLCB637.18|ML1698 HYPOTHETICAL 29.5 KDA PROTEIN
                     from Mycobacterium leprae (277 aa), FASTA scores: opt:
                     1245, E(): 1.2e-65, (70.5% identity in 278 aa overlap).
                     Also similar, but longer 100 aa in N-terminus, to other
                     hypothetical proteins, few membrane proteins, e.g.
                     Q9RKN9|SCC75A.35 PUTATIVE MEMBRANE PROTEIN from
                     Streptomyces coelicolor (180 aa), FASTA scores: opt: 326,
                     E(): 3.9e-12, (44.2% identity in 138 aa overlap);
                     P96694|YDFP|AB001488 HYPOTHETICAL PROTEIN from Bacillus
                     subtilis (129 aa), FASTA scores: opt:273, E(): 3.7e-09,
                     (33.1% identity in 130 aa overlap); Q9KKT1|VCA1019
                     HYPOTHETICAL PROTEIN from Vibrio cholerae (148 aa), FASTA
                     scores: opt: 258, E(): 3.1e-08, (34.9% identity in 126 aa
                     overlap); etc. Mb3030c found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:A0A1R3Y2V3"
                     /db_xref="InterPro:IPR032808"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y2V3"
BEGIN
        1 MTSSNDSHWQ RPDDSPGPMP GRPVSASLVD PEDDLTPARY AGDFGSGTTT VIPPYDAASS
       61 GVGNSGYSLI EAAEPLPYVQ PQPGRQVPAG SAGIDMDDDE RVRAAGRRGT QNLGLLILRV
      121 GLGAVLIAHG LQKLFGWWDG QGLAGFQNSL SDIGYQHAEI LAYVSAGGEI VAGVLLVLGL
      181 FTPLAAAGAL AFLINGLLAG ISAQHSRPVA YFLQDGHEYQ ITLVVMAVAV ILSGPGRYGL
      241 DAARGWAHRP FIGSFVALLG GIAAGIAVWV LLNGANPLA
//