LOCUS SIU01649.1 219 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN protein. ACCESSION LT708304-3063 PROTEIN_ID SIU01649.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB3025" /note="Mb3025, -, len: 219 aa. Equivalent to Rv3000, len: 219 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 219 aa overlap). Possible conserved transmembrane protein, similar to various membrane proteins e.g. P77307|YBBM_ECOLI|B0491 HYPOTHETICAL 28.2 KDA PROTEIN (POTENTIAL INTEGRAL MEMBRANE PROTEIN) from Escherichia coli strain K12 (259 aa), FASTA scores: opt: 292, E(): 3.1e-11, (30.25% identity in 218 aa overlap); N-terminus of Q9BJF3 PUTATIVE ABC TRANSPORTER (FRAGMENT) from Sterkiella histriomuscorum (1319 aa), FASTA scores: opt: 274, E(): 1.3e-09, (39.6% identity in 101 aa overlap); Q9C9W0|T23K23.21 PUTATIVE ABC TRANSPORTER from Arabidopsis thaliana (Mouse-ear cress) (263 aa), FASTA scores: opt: 258, E(): 4.4e-09, (30.1% identity in 196 aa overlap); P74369|YG47_SYNY3|SLR1647 HYPOTHETICAL 28.1 KDA PROTEIN (POTENTIAL INTEGRAL MEMBRANE PROTEIN) from Synechocystis sp. strain PCC 6803 (259 aa), FASTA scores: opt: 257, E(): 5.1e-09, (37.75% identity in 98 aa overlap); etc. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Mb3025 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:A0A1R3Y2T4" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR005226" /db_xref="InterPro:IPR027417" /db_xref="UniProtKB/TrEMBL:A0A1R3Y2T4" BEGIN 1 MAVHGFLLER VSVVRDEATV LRQVSAHFPA GRCSAVRGAS GSGKTTLLRL LNRLIDPTSG 61 KVWLDGVPLT DLDVLVLRRR VGLVAQAPVV LTDAVLNEVR VGRPDLPEGR VTELLARLCL 121 GQSAREAFLP HQRSALRTAL IPAIDSTKVV GLISLPGAMS GLILAGVDPL TAIRYQIVVM 181 YLLLAATAVA ALTCARLAER ALFDRAHRLV SLPAATRRA //