LOCUS       SIU01649.1               219 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE
            CONSERVED TRANSMEMBRANE PROTEIN protein.
ACCESSION   LT708304-3063
PROTEIN_ID  SIU01649.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB3025"
                     /note="Mb3025, -, len: 219 aa. Equivalent to Rv3000, len:
                     219 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 219 aa overlap). Possible conserved
                     transmembrane protein, similar to various membrane
                     proteins e.g. P77307|YBBM_ECOLI|B0491 HYPOTHETICAL 28.2
                     KDA PROTEIN (POTENTIAL INTEGRAL MEMBRANE PROTEIN) from
                     Escherichia coli strain K12 (259 aa), FASTA scores: opt:
                     292, E(): 3.1e-11, (30.25% identity in 218 aa overlap);
                     N-terminus of Q9BJF3 PUTATIVE ABC TRANSPORTER (FRAGMENT)
                     from Sterkiella histriomuscorum (1319 aa), FASTA scores:
                     opt: 274, E(): 1.3e-09, (39.6% identity in 101 aa
                     overlap); Q9C9W0|T23K23.21 PUTATIVE ABC TRANSPORTER from
                     Arabidopsis thaliana (Mouse-ear cress) (263 aa), FASTA
                     scores: opt: 258, E(): 4.4e-09, (30.1% identity in 196 aa
                     overlap); P74369|YG47_SYNY3|SLR1647 HYPOTHETICAL 28.1 KDA
                     PROTEIN (POTENTIAL INTEGRAL MEMBRANE PROTEIN) from
                     Synechocystis sp. strain PCC 6803 (259 aa), FASTA scores:
                     opt: 257, E(): 5.1e-09, (37.75% identity in 98 aa
                     overlap); etc. Contains PS00017 ATP/GTP-binding site motif
                     A (P-loop). Mb3025 found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:A0A1R3Y2T4"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR005226"
                     /db_xref="InterPro:IPR027417"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y2T4"
BEGIN
        1 MAVHGFLLER VSVVRDEATV LRQVSAHFPA GRCSAVRGAS GSGKTTLLRL LNRLIDPTSG
       61 KVWLDGVPLT DLDVLVLRRR VGLVAQAPVV LTDAVLNEVR VGRPDLPEGR VTELLARLCL
      121 GQSAREAFLP HQRSALRTAL IPAIDSTKVV GLISLPGAMS GLILAGVDPL TAIRYQIVVM
      181 YLLLAATAVA ALTCARLAER ALFDRAHRLV SLPAATRRA
//