LOCUS SIU01648.1 321 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE CONSERVED LIPOPROTEIN LPPY protein. ACCESSION LT708304-3062 PROTEIN_ID SIU01648.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="lppY" /locus_tag="BQ2027_MB3024" /note="Mb3024, lppY, len: 321 aa. Equivalent to Rv2999, len: 321 aa, from Mycobacterium tuberculosis strain H37Rv, (99.7% identity in 321 aa overlap). Probable lppY, conserved lipoprotein, highly similar to O07774|LPQO|Rv0604|MTCY19H5.18c PUTATIVE LIPOPROTEIN from Mycobacterium tuberculosis (316 aa), FASTA scores: opt: 1153, E(): 5e-62, (53.2% identity in 312 aa overlap); and showing similarity with AAK80743|CAC2799 UNCHARACTERIZED CONSERVED PROTEIN SIMILAR TO LPPY/LPQO OF Mycobacterium tuberculosis from Clostridium acetobutylicum (152 aa), FASTA scores: opt: 165, E(): 0.0077, (26.08% identity in 138 aa overlap); and Q9F2T1|SCD65.01c PUTATIVE LIPOPROTEIN (FRAGMENT) from Streptomyces coelicolor (146 aa), FASTA scores: opt: 126, E(): 1.6, (% identity in aa overlap). Equivalent to AAK47407 from Mycobacterium tuberculosis strain CDC1551 (329 aa) but shorter 8 aa. Contains probable N-terminal signal sequence and PS00013 Prokaryotic membrane lipoprotein lipid attachment site. Protein product from Mb3024 detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb3024 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing (TPM > 20)." /db_xref="InterPro:IPR011094" /db_xref="UniProtKB/TrEMBL:A0A1R3Y379" BEGIN 1 MAGAKHAGRI VAITTAAAVI LAACSSGSKG GAGSGHAGKA RSAVTTTDAD WKPVADALGR 61 SGKLGDNNTA YRINLPRNDL HITSYGVDIK PGLSLGGYAA FARYDNNETL LMGDLVITEE 121 ELPKVTDALQ AHGIAQTALH KHLLQQDPPV WWTHIHGMGD AARLAQGLKA ALDATTIGPP 181 TPPPARQPPV DIDVAGVDQA LGRKGTQDGG LLKYSIPRKD TIIEDGHVLP AVSLNLTTVI 241 NFQPVGRGRA AINGDFILIA PEVQEVIRAM RAGNITIVEL HNHGLTEEPR LFYMHYWAVD 301 DAVTLARALR PAMDATNLQS S //