LOCUS       SIU01648.1               321 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            CONSERVED LIPOPROTEIN LPPY protein.
ACCESSION   LT708304-3062
PROTEIN_ID  SIU01648.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="lppY"
                     /locus_tag="BQ2027_MB3024"
                     /note="Mb3024, lppY, len: 321 aa. Equivalent to Rv2999,
                     len: 321 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.7% identity in 321 aa overlap). Probable lppY,
                     conserved lipoprotein, highly similar to
                     O07774|LPQO|Rv0604|MTCY19H5.18c PUTATIVE LIPOPROTEIN from
                     Mycobacterium tuberculosis (316 aa), FASTA scores: opt:
                     1153, E(): 5e-62, (53.2% identity in 312 aa overlap); and
                     showing similarity with AAK80743|CAC2799 UNCHARACTERIZED
                     CONSERVED PROTEIN SIMILAR TO LPPY/LPQO OF Mycobacterium
                     tuberculosis from Clostridium acetobutylicum (152 aa),
                     FASTA scores: opt: 165, E(): 0.0077, (26.08% identity in
                     138 aa overlap); and Q9F2T1|SCD65.01c PUTATIVE LIPOPROTEIN
                     (FRAGMENT) from Streptomyces coelicolor (146 aa), FASTA
                     scores: opt: 126, E(): 1.6, (% identity in aa overlap).
                     Equivalent to AAK47407 from Mycobacterium tuberculosis
                     strain CDC1551 (329 aa) but shorter 8 aa. Contains
                     probable N-terminal signal sequence and PS00013
                     Prokaryotic membrane lipoprotein lipid attachment site.
                     Protein product from Mb3024 detected using shotgun mass
                     spectrometry and SWATH mass spectrometry. Mb3024 found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing (TPM > 20)."
                     /db_xref="InterPro:IPR011094"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y379"
BEGIN
        1 MAGAKHAGRI VAITTAAAVI LAACSSGSKG GAGSGHAGKA RSAVTTTDAD WKPVADALGR
       61 SGKLGDNNTA YRINLPRNDL HITSYGVDIK PGLSLGGYAA FARYDNNETL LMGDLVITEE
      121 ELPKVTDALQ AHGIAQTALH KHLLQQDPPV WWTHIHGMGD AARLAQGLKA ALDATTIGPP
      181 TPPPARQPPV DIDVAGVDQA LGRKGTQDGG LLKYSIPRKD TIIEDGHVLP AVSLNLTTVI
      241 NFQPVGRGRA AINGDFILIA PEVQEVIRAM RAGNITIVEL HNHGLTEEPR LFYMHYWAVD
      301 DAVTLARALR PAMDATNLQS S
//